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Latest Nanopore Stories

2012-01-10 23:21:53

New method for nucleic acid analysis In the world of biomolecules such as proteins and the hereditary nucleic acids DNA and RNA, three-dimensional structure determines function. Analysis of the passage of such molecules through nanopores offers a relatively new, but highly promising, technique for obtaining information about their spatial conformations. However, interactions between the test molecules and the proteins used as pores have so far hindered quantitative analysis of the behavior...

2011-09-15 20:22:55

Nanotechnology sensor could lead to earlier diagnosis for world's deadliest form of cancer When lung cancer strikes, it often spreads silently into more advanced stages before being detected. In a new article published in Nature Nanotechnology, biological engineers and medical scientists at the University of Missouri reveal how their discovery could provide a much earlier warning signal. "Early detection can save lives, but there is currently no proven screening test available for lung...

2011-06-20 19:50:39

Researchers at Delft University of Technology and the University of Basel have established a biomimetic nanopore that provides a unique test and measurement platform for the way that proteins move into a cell's nucleus. In the journal Nature Nanotechnology (June 19 - online), they report an artificial nanopore that is functionalized with key proteins which mimicks the natural nuclear pore. Upon testing the transport of individual proteins through the biomimetic pore, they found that most...

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2011-05-24 06:21:46

Sequencing DNA base pairs "“ the individual molecules that make up DNA "“ is key for medical researchers working toward personalized medicine. Being able to isolate, study and sequence these DNA molecules would allow scientists to tailor diagnostic testing, therapies and treatments based on each patient's individual genetic makeup. But being able to isolate individual molecules like DNA base pairs, which are just two nanometers across "“ or about 1/50,000th the diameter of a...

2011-04-06 23:18:10

Researchers at Rensselaer Polytechnic Institute Discover New Method To Boost Enzymatic Activity Proteins are critically important to life and the human body. They are also among the most complex molecules in nature, and there is much we still don't know or understand about them. One key challenge is the stability of enzymes, a particular type of protein that speeds up, or catalyzes, chemical reactions. Taken out of their natural environment in the cell or body, enzymes can quickly lose their...

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2011-03-01 09:42:42

By mimicking the structure of the silk moth's antenna, University of Michigan researchers led the development of a better nanopore"”a tiny tunnel-shaped tool that could advance understanding of a class of neurodegenerative diseases that includes Alzheimer's. A paper on the work is newly published online in Nature Nanotechnology. This project is headed by Michael Mayer, an associate professor in the U-M departments of Biomedical Engineering and Chemical Engineering. Also collaborating...

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2010-12-20 11:32:19

Scientists from Imperial College London are developing technology that could ultimately sequence a person's genome in mere minutes, at a fraction of the cost of current commercial techniques. The researchers have patented an early prototype technology that they believe could lead to an ultrafast commercial DNA sequencing tool within ten years. Their work is described in a study published this month in the journal Nano Letters and it is supported by the Wellcome Trust Translational Award and...

2010-12-01 22:54:50

Genome sequencing will have a profound effect on our understanding of genetic biology and could usher in a day when doctor and patient are able to review individual genome sequences to fully personalise medical treatment. As the X PRIZE FOUNDATION begins to receive nominations for its $10m prize for the first privately funded company that can accurately sequence 100 genomes in 10 days for less than $10,000 per genome, the science writer Philip Ball looks at the latest advances towards success...

2010-11-15 13:34:12

The twisting, ladder-like form of the DNA molecule"”the architectural floor plan of life"”contains a universe of information critical to human health. Enormous effort has been invested in deciphering the genetic code, including, most famously, the Human Genome Project. Nevertheless, the process of reading some three-billion nucleotide "letters" to reveal an individual's full genome remains a costly and complex undertaking. Now biophysicist Stuart Lindsay, of the Biodesign...


Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.