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Latest Nanopore Stories

2010-05-20 15:20:00

Boston University biomedical engineers develop new nanopore method for DNA sequencing Sequencing DNA could get a lot faster and cheaper "“ and thus closer to routine use in clinical diagnostics "“ thanks to a new method developed by a research team based at Boston University. The team has demonstrated the first use of solid state nanopores "” tiny holes in silicon chips that detect DNA molecules as they pass through the pore "” to read the identity of the four...

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2010-04-28 11:20:27

Using a pair of exotic techniques including a molecular-scale version of ice fishing, a team of researchers working at the National Institute of Standards and Technology (NIST) have developed methods to measure accurately the length of "nanopores," the miniscule channels found in cell membranes. The "molecular rulers" they describe in a recent paper* could serve as a way to calibrate tailor-made nanopores"”whose diameters on average are nearly 10,000 times smaller than that of a human...

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2010-01-01 10:50:00

Faster sequencing of DNA holds enormous potential for biology and medicine, particularly for personalized diagnosis and customized treatment based on each individual's genomic makeup. At present however, sequencing technology remains cumbersome and cost prohibitive for most clinical applications, though this may be changing, thanks to a range of innovative new techniques. In the current issue of Science, Stuart Lindsay, director of Arizona State University's Center for Single Molecule...

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2009-12-20 13:15:00

Boston University biomedical engineers have devised a method for making future genome sequencing faster and cheaper by dramatically reducing the amount of DNA required, thus eliminating the expensive, time-consuming and error-prone step of DNA amplification. In a study published in the Dec. 20 online edition of Nature Nanotechnology, a team led by Boston University Biomedical Engineering Associate Professor Amit Meller details pioneering work in detecting DNA molecules as they pass through...

2009-10-12 13:18:00

YORKTOWN HEIGHTS, N.Y., Oct. 12 /PRNewswire-FirstCall/ -- IBM Research (NYSE: IBM) today announced it has received an "Advanced Sequencing Technology Award" from the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, to design a silicon-based "DNA Transistor" that will advance genome sequencing technology and generate progress in health care diagnosis and practice. (Logo: http://www.newscom.com/cgi-bin/prnh/20090416/IBMLOGO) View video:...

2009-10-05 23:01:00

YORKTOWN HEIGHTS, N.Y., Oct. 6 /PRNewswire-FirstCall/ -- In an effort to build a nanoscale DNA sequencer, IBM (NYSE: IBM) scientists are drilling nano-sized holes in computer-like chips and passing DNA strands through them in order to read the information contained within their genetic code. View video: http://www.youtube.com/watch?v=pKi30ai35mU View animation: http://www.youtube.com/watch?v=wvclP3GySUY For an ongoing conversation on this research project, visit the Smarter...

2009-09-28 12:14:26

Using an RNA-powered nanomotor, University of Cincinnati (UC) biomedical engineering researchers have successfully developed an artificial pore able to transmit nanoscale material through a membrane. In a study led by UC biomedical engineering professor Peixuan Guo, PhD, members of the UC team inserted the modified core of a nanomotor, a microscopic biological machine, into a lipid membrane. The resulting channel enabled them to move both single- and double-stranded DNA through the membrane....

2009-06-08 15:25:27

U.S. scientists are developing a solid-state genome sequencing sensor that could ultimately perform DNA analysis with a single molecule. University of Illinois researchers said their nanopore sensor, made by drilling a tiny hole through a thin film of aluminum oxide, could offer tremendous possibilities for personalized medicine and advanced diagnostics. Solid-state nanopore sensors have shown superior chemical, thermal and mechanical stability over their biological counterparts, and can be...

2009-06-02 11:27:05

Fast and affordable genome sequencing has moved a step closer with a new solid-state nanopore sensor being developed by researchers at the University of Illinois.The nanopore sensor, made by drilling a tiny hole through a thin film of aluminum oxide, could ultimately prove capable of performing DNA analysis with a single molecule, offering tremendous possibilities for personalized medicine and advanced diagnostics."Solid-state nanopore sensors have shown superior chemical, thermal and...

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2009-04-16 08:00:04

Physicists at Brown University have developed a novel procedure to map a person's genome. They report in the journal Nanotechnology the first experiment to move a DNA chain through a nanopore using magnets. The approach is promising because it allows multiple segments of a DNA strand to be read simultaneously and accurately. Since the human genome was sequenced six years ago, the cost of producing a high-quality genome sequence has dropped precipitously. More recently, the National Institutes...


Word of the Day
omadhaun
  • A fool; a simpleton: a term of abuse common in Ireland and to a less extent in the Gaelic-speaking parts of Scotland.
This word is partly Irish in origin.