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Last updated on April 25, 2014 at 1:22 EDT

Latest narcolepsy Stories

2009-05-13 06:30:00

DURHAM, N.C., May 13 /PRNewswire/ -- Addrenex Pharmaceuticals today expanded its pipeline of products aimed at adrenergic regulation with the signing of an agreement to license a new drug for the treatment of narcolepsy, a chronic and debilitating sleep disorder, as well as other neurologic and psychiatric conditions. The agreement to license ADX-N05 gives Addrenex the worldwide rights (excluding East Asia) to develop, manufacture and commercialize the compound from SK Life Science Business...

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2009-05-04 07:12:14

Ten years ago, Stanford University School of Medicine scientist Emmanuel Mignot, MD, PhD, and his colleagues made headlines when they identified the culprit behind the sleep disorder narcolepsy. Now Mignot and his collaborators have shown for the first time that a specific immune cell is involved in the disorder "” confirming experts' long-held suspicion that narcolepsy is an autoimmune disease. The work, which will be published online May 3 in Nature Genetics, could lead to better...

2009-03-17 13:57:00

Driving hazards caused by sleepiness highlighted on World Sleep Day NEW YORK, March 17 /PRNewswire-USNewswire/ -- Improved diagnosis and treatment of sleep disorders could help to cut fatal or serious road traffic accidents by up to one third, according to the World Association of Sleep Medicine. The announcement has been made on the second annual World Sleep Day, March 20, an international event aimed at raising awareness of the burden and impact of sleep disorders. World Sleep Day is an...

2009-01-29 14:28:30

Falling asleep involuntarily during the day poses a very real and dangerous problem, Canadian researchers said. Researchers at the Montreal Neurological Institute at McGill University demonstrates sleep-wake states are regulated by two types of nerve cells, melanin-concentrating hormone neurons and orexin neurons, which occupy the same region of the brain, but perform opposite functions. The study is the first to discover that melanin-concentrating hormone neurons are activated during sleep...

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2009-01-29 09:56:29

Lack of sleep is a common complaint but for many, falling asleep involuntarily during the day poses a very real and dangerous problem. A new study from the Montreal Neurological Institute (MNI) at McGill University demonstrates interestingly, that sleep-wake states are regulated by two different types of nerve cells (neurons), melanin-concentrating hormone (MCH) neurons and orexin (Orx) neurons, which occupy the same region of the brain but perform opposite functions. The MNI study is the...

2009-01-28 09:40:00

Mice with increased levels of a natural brain chemical don't gain weight when fed a high-fat diet, researchers at UT Southwestern Medical Center have found. The chemical, orexin, works by increasing the body's sensitivity to the "weight-loss hormone," leptin, the researchers report. Finding a way to boost the orexin system may prove useful as a therapy against obesity, said Dr. Masashi Yanagisawa, professor of molecular genetics at UT Southwestern and senior author of the study, which appears...

2009-01-13 07:30:00

PALO ALTO, Calif., Jan. 13 /PRNewswire-FirstCall/ -- Jazz Pharmaceuticals, Inc. (Nasdaq: JAZZ) today announced completion of enrollment in the second of two Phase III pivotal clinical trials of JZP-6 (sodium oxybate) for the treatment of fibromyalgia. "Completion of enrollment in this second trial is a meaningful milestone in the JZP-6 program in fibromyalgia. We expect to report top-line results from this trial in mid-2009," said Samuel Saks, M.D., Chief Executive Officer. The...

2009-01-05 08:38:15

An unusual sleep disorder could be a precursor to dementia or Parkinson's disease. Patients with REM sleep behavior disorder have excessive muscle activity during REM sleep -- often called the dream stage of sleep -- causing them to punch, kick or cry out when they are in a deep sleep. Of the 93 REM sleep behavior patients involved in the study, 26 developed a neurodegenerative disease within five years. Doctors estimate the 10-year disease development risk to be 41 percent and the 12-year...

2008-12-25 09:02:16

 People with a sleep disorder that causes them to kick or cry out during their sleep may be at greater risk of developing dementia or Parkinson's disease, according to a study published in the December 24, 2008, online issue of Neurology®, the medical journal of the American Academy of Neurology.The sleep disorder is called REM sleep behavior disorder. People with the disorder do not have the normal lack of muscle tone that occurs during REM sleep, often known as the...

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2008-11-27 09:50:41

In a novel study appearing this week in Neuron, Brandeis researchers identify for the first time a specific set of wake-promoting neurons in fruit flies that are analogous to cells in the much more complex sleep circuit in humans. The study demonstrates that in flies, as in mammals, the sleep circuit is intimately linked to the circadian clock and that the brain's strategies to govern sleep are evolutionarily ancient. In the study, researchers quieted ventral lateral neurons (LNvs) and...