Latest National Institute for Physiological Sciences Stories
Researchers at the Institute for Comprehensive Medical Science, Fujita Health University and the National Institute for Physiological Sciences, Japan, along with colleagues from 9 other institutions, have identified an exceptional mouse model of schizophrenia.
In the brains of humans and non-human primates, over 100 billion nerve cells build up complicated neural circuits and produce higher brain functions.
The collaborative research team led by Professor Tadashi ISA, Project Assistant Professor Masaharu KINOSHITA from The National Institute for Physiological Sciences, The National Institutes of Natural Sciences and Fukushima Medical University and Kyoto University, developed "the double viral vector transfection technique" which can deliver genes to a specific neural circuit by combining two new kinds of gene transfer vectors.
Macrophages playing an important role in the immune system eat and fight against pathogens and foreign substances in the very beginning of infection.
The mechanism involved in the detection of hyperosmolarity by TRP channels is clarified, with a newly discovered molecule preventing apoptosis.
The research group headed by Professor Atsushi Nambu (The National Institute for Physiological Sciences) and Professor Masahiko Takada (Primate Research Institute, Kyoto University) has shown that the 'oscillatory' nature of electrical signals in subcortical nuclei, the basal ganglia, causes severe motor deficits in Parkinson's disease, by disturbing the information flow of motor commands.
An effective recovery has been observed in stroke patients and those with spinal cord injuries who have strong vitality and motivation to rehabilitate in clinical practice.
Neurons in the brain play a role as an electric wire conveying an electrical signal.
Recently, optogenetics, which controls the activity of neuron using the light-activated protein, has been getting a lot of attention.
The animals on the earth have adapted themselves to the environmental temperature changes such as hot in deserts, or cold in the glacial epochs.
- A volcanic mudflow.