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Latest National Institute of General Medical Sciences Stories

2010-04-19 08:13:03

A new discovery about the wound-healing process could lead to better treatments for diabetics and other patients who have wounds that are slow to heal. Loyola University Health System researchers found that certain immune system cells slow the wound-healing process. Thus, it might be possible to improve healing by inactivating these immune system cells, said Elizabeth Kovacs, PhD, who heads the laboratory team that made the discovery. The findings by Kovacs and colleagues are reported online,...

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2010-03-31 13:46:44

Did you know that filling out your census card will help computer scientists model how diseases spread in the United States? Over the last four years, researchers at RTI International in North Carolina have been transforming data from the 2000 census"”which described the country's 281 million people and 116 million households"”into a virtual U.S. population. They finished the "synthetic population" last year, and they plan to update it when the 2010 census results come out. The...

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2010-03-18 09:05:00

University of Chicago scientists have successfully used geometrically patterned surfaces to influence the development of stem cells. The new approach is a departure from that of many stem-cell biologists, who focus instead on uncovering the role of proteins in controlling the fate of stem cells. "The cells are seeing the same soluble proteins. In both cases it's the shape alone that's dictating whether they turn into fat or bone, and that hasn't been appreciated before," said Milan Mrksich,...

2010-02-24 09:00:00

Partnership Combines Strengths to Speed New Treatments to Patients WASHINGTON, Feb. 24 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration and the National Institutes of Health today unveiled an initiative designed to accelerate the process from scientific breakthrough to the availability of new, innovative medical therapies for patients. (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO) The initiative involves two interrelated scientific disciplines:...

2010-02-23 10:07:13

Rate of T cell drop not helpful in decision to start treating HIV In research published this week in PLoS Medicine, Susan Huang and colleagues describe the use of a novel automated cluster detection tool, WHONET-SaTScan, made by integrating two freely available software packages, to identify hospital infection clusters. After applying the software to microbiology data from patients admitted to a 750-bed academic medical center in the US across four years (2002-2006), the authors found that...

2009-08-27 07:38:57

A new study reports that as many as 30 percent of people taking Plavix, one of the world's best-selling medicines, respond negatively to the drug and are at risk for stroke and heart attack. Plavix is meant to prevent blood clots in people with heart disease by keeping platelets from sticking together. Researchers at the National Institute of General Medical Sciences (NIGMS) at the National Institutes of Health (NIH) performed a genome-wide association study in two distinct populations,...

2009-08-25 15:28:05

 A new study reports that a gene variant carried by about a third of the population plays a major role in this group's response to an anti-clotting medicine, clopidogrel (Plavix). People with the variant produce a defective version of the CYP2C19 enzyme and are less able to activate the drug.One of the world's best-selling medicines, Plavix prevents blood clots in people with heart disease by keeping platelets from sticking together. But about 30 percent of people respond poorly to the...

2009-08-13 07:18:40

Drs. Gayle Slaughter, assistant dean of graduate education in the graduate school of biomedical sciences at Baylor College of Medicine, and Michael J. Friedlander, chair of the department of neuroscience and director of neuroscience initiatives at BCM, were awarded National Institute of General Medical Sciences' funding from the National Institutes of Health through the American Recovery and Reinvestment Act.The two awards, $240,969 and $136,816 respectively, will be used over the next two...

2009-03-27 09:49:18

A research team at the Scripps Research Institute has obtained the first glimpse of a protein that keeps certain substances, including many drugs, out of cells. The protein, called P-glycoprotein or P-gp for short, is one of the main reasons cancer cells are resistant to chemotherapy drugs. Understanding its structure may help scientists design more effective drugs. The new research was described in the March 27, 2009, issue of the journal Science. "This structure is an important advance and...

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2009-03-26 16:22:50

Scientists have reported discovering a new technique of developing human skin cells to carry properties of powerful embryonic stem cells. Dr James A. Thomson, of the University of Wisconsin-Madison, led a team of researchers to use a process known as pluripotency to endow various cells with the capacity to develop into any of the roughly 220 types of cells. Scientists have previously reported some success with pluripotency techniques, but Thomson's research marks the first time scientists...


Word of the Day
bibliopole
  • A bookseller; now, especially, a dealer in rare and curious books.
This word comes from a Greek phrase meaning 'book seller.'
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