Latest National Institute of Neurological Disorders and Stroke Stories

NIH study also shows that overall stroke risk is down from 10 years ago Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health. Lacunar strokes occur due to chronic high blood pressure and typically produce small lesions deep within the brain....

NIH-funded study shows cells from different patients have unique drug responses Researchers have taken a step toward personalized medicine for Parkinson's disease, by investigating signs of the disease in patient-derived cells and testing how the cells respond to drug treatments. The study was funded by the National Institutes of Health. The researchers collected skin cells from patients with genetically inherited forms of Parkinson's and reprogrammed those cells into neurons. They...

AMSTERDAM, June 21, 2012 /PRNewswire/ -- uniQure, a leader in the field of human gene therapy, announced today the signing of a collaborative agreement with two leading neurology experts to develop further a gene therapy incorporating uniQure's GDNF (glial cell derived neurotrophic factor) gene for the treatment of Parkinson's disease. Professor Krystof Bankiewicz at the University of California, San Francisco (UCSF), a world expert in GDNF gene therapy, and Professor...

GRAND RAPIDS, Mich., June 19, 2012 /PRNewswire/ -- Tetra Discovery Partners LLC, a leader in the design of new treatments for major neurological conditions based on PDE4 modulation in the brain, today announced it has been awarded a five-year cooperative agreement by the National Institutes of Health (NIH). The award will support Tetra's efforts to develop a new drug to treat mild cognitive impairment, which is typically associated with aging and often precedes and accompanies...

HOUSTON, June 7, 2012 /PRNewswire-USNewswire/ -- The Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital (NRI), one of the world's first basic research institutes dedicated to childhood neurological diseases, recently joined with Genentech, Inc. and the journal Science Translational Medicine, to stage an international symposium on disorders of synaptic dysfunction - a growing class of neurological disorders including autism. Leaders from around the world in...

Findings offer a fresh look at developmental and degenerative brain diseases BOSTON, May 23, 2012 /PRNewswire-USNewswire/ -- We're born with our brains prewired, but as information comes in from our environment, this circuitry is updated. A study from Boston Children's Hospital provides a new glimpse of how this happens: Brain cells known as microglia, tuned into the crosstalk between neurons, literally engulf unnecessary connections, known as synapses, and prune them away. The...

SYOSSET, N.Y., April 13, 2012 /PRNewswire/ -- Ms. Joan L. Barrick of Bethesda, Maryland has been included in the Strathmore's Who's Who Worldwide Edition for her outstanding contributions and achievements in the field of Government and Research. About JOAN BARRICK Ms. Barrick has over 35 years in biological research experience. She has been with NINDS/NIH for 24 years. She currently works in Dr. Richard Youle's lab. She helps maintain a bank of plasmids used in experiments that...

Kessler Foundation stroke expert co-chairs review of rehabilitation and recovery; working group sets priorities for future research In 2011, the National Institute of Neurological Disorders and Stroke (NINDS) convened the Stroke Progress Review Group (SPRG) to conduct a final 10-year review of the state of stroke research. The goal is to set priorities and shape future NINDS programs and policies.  While SPRG found much available data for maximizing stroke rehabilitation effects,...

Kupferberg to be Honored at Third Biennial Epilepsy Pipeline Update Conference 2012 in San Francisco February 2-4 WASHINGTON, Jan. 11, 2012 /PRNewswire-USNewswire/ -- The Epilepsy Therapy Project (ETP), a non-profit organization whose mission is to accelerate new therapies for people living with epilepsy and seizures and the parent organization of epilepsy.com, today announced that Harvey Kupferberg, Ph.D., has been named the recipient of the ETP Lifetime Accelerator Award in...

NEW YORK, Nov. 16, 2011 /PRNewswire/ -- The New York Academy of Sciences (NYAS) and One Mind for Research announced the creation of a new partnership initiative to improve the productivity of biomedical research and development for Alzheimer's disease and dementia, diseases that represent a significant and growing burden on healthcare systems and families. The partnership is a major initiative for One Mind for Research, a program that brings together public and private partners with the...