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Latest Nature Biotechnology Stories

2014-04-28 10:17:33

A next-generation genome editing system developed by Massachusetts General Hospital (MGH) investigators substantially decreases the risk of producing unwanted, off-target gene mutations. In a paper receiving online publication in Nature Biotechnology, the researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites. "This system combines the ease of use of the widely...

2014-01-27 14:42:53

Cancer is the leading cause of death in Canada and is responsible for about 30% of all deaths, according to the Canadian Cancer Society. Despite the urgent need for new and effective drugs, it remains extremely difficult to develop anti-cancer therapies in a timely way. Researchers in Ottawa looked at how to leverage current experimental therapies, in different combinations, to speed the fight against cancer. Scientific evidence suggests a specific combination approach is effective, as...

2013-09-16 11:33:23

European scientists, led by researchers from the University of Geneva (UNIGE)'s Faculty of Medicine in the context of the GEUVADIS project, today present a map that points to the genetic causes of differences between people. The study, published in Nature and Nature Biotechnology, offers the largest-ever dataset linking human genomes to gene activity at the level of RNA. Understanding how each person's unique genome makes them more or less susceptible to disease is one of the biggest...

2013-09-09 08:58:36

A team of scientists at Karolinska Institutet and Harvard University has taken a major step towards treatment for heart attack, by instructing the injured heart in mice to heal by expressing a factor that triggers cardiovascular regeneration driven by native heart stem cells. The study, published in Nature Biotechnology, also shows that there was an effect on driving the formation of a small number of new cardiac muscle cells. "This is the beginning of using the heart as a factory to...

2013-05-20 11:20:27

May allow doctors to track progression of cancer, response to treatment, and risk of relapse In their quest to learn more about the variability of cells between and within tissues, biomedical scientists have devised tools capable of simultaneously measuring dozens of characteristics of individual cells. These technologies have led to new challenges, however, as scientists now struggle with how to make sense of the resulting trove of data. Now a solution may be at hand. Researchers at...

2013-04-22 16:56:17

Sweeping study of cancer metabolism identifies hundreds of alterations and potential drug targets to starve tumors A massive study analyzing gene expression data from 22 tumor types has identified multiple metabolic expression changes associated with cancer. The analysis, conducted by researchers at Columbia University Medical Center, also identified hundreds of potential drug targets that could cut off a tumor's fuel supply or interfere with its ability to synthesize essential building...

2012-12-13 05:00:04

Strategy Overview on Biotech Products Highlights Emerging Trends and Competitive Dynamics Bethesda, Maryland (PRWEB) December 12, 2012 Novel Health Strategies LLC, a leading life sciences consulting firm announces the publication of 2011-2012 market trends study called 'What's fueling the biotech engine-2011 to 2012', in Nature Biotechnology. The published article is an analysis of sales, pricing, HEOR, reimbursement trends and competitive dynamics of more than hundred specialty biologic...

2012-08-27 11:50:37

Novel vaccine additive to enhance the body's immune response shows promise in mice Oxford University scientists have discovered a compound that greatly boosts the effect of vaccines against viruses like flu, HIV and herpes in mice. An 'adjuvant' is a substance added to a vaccine to enhance the immune response and offer better protection against infection. The Oxford University team, along with Swedish and US colleagues, have shown that a type of polymer called polyethyleneimine (PEI)...

2012-07-23 20:39:37

Applications include studying single cells that form malignant tumors Only by viewing a Seurat painting at close range can you appreciate the hidden complexities of pointillism — small, distinct dots of pure color applied in patterns to form an image from a distance. Similarly, biologists and geneticists have long sought to analyze profiles of genes at the single cell level but technology limitations have only allowed a view from afar until now. Research published in the July 22...

2012-07-23 10:53:32

A new technique will allow plant breeders to introduce valuable crop traits even without access to the full genome sequence of that crop. The technique, published in the journal Nature Biotechnology, links important agronomic traits in crop plants with active regions of the genome. Instead of requiring knowledge of the crop's complete genome, it identifies only expressed genes. "For many crop plants, markers are still lacking because of the complexity of some plants' genomes and the...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
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