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Latest Nature Biotechnology Stories

2012-06-25 16:35:59

The blood-brain barrier -- the filter that governs what can and cannot come into contact with the mammalian brain -- is a marvel of nature. It effectively separates circulating blood from the fluid that bathes the brain, and it keeps out bacteria, viruses and other agents that could damage it. But the barrier can be disrupted by disease, stroke and multiple sclerosis, for example, and also is a big challenge for medicine, as it can be difficult or impossible to get therapeutic molecules...

2012-06-01 09:56:20

New Weizmann Institute technology speeds up DNA “rewriting” and measures the effects of the changes in living cells Our ability to “read” DNA has made tremendous progress in the past few decades, but the ability to understand and alter the genetic code, that is, to “rewrite” the DNA-encoded instructions, has lagged behind. A new Weizmann Institute study advances our understanding of the genetic code: It proposes a way of effectively introducing numerous...

2012-05-14 22:29:30

Arranging DNA fragments into a genome sequence that scientists can interpret is a challenge often compared to assembling a puzzle except you don´t have the box and have no idea what the picture is supposed to be. Sometimes clues from other publicly-available DNA sequences of related organisms can be used to guide the assembly process, but its usefulness depends on how closely related any two sequences are to one another. For example, a reference genome might be so distantly related from...

2012-03-27 00:46:14

Joint BioEnergy Institute Researchers Develop Dynamic System for Regulating Metabolic Pathways Significant boosts in the microbial production of clean, green and renewable biodiesel fuel has been achieved with the development of a new technique in synthetic biology by researchers with the U.S. Department of Energy (DOE)´s Joint BioEnergy Institute (JBEI). This new technique — dubbed a dynamic sensor-regulator system (DSRS) — can detect metabolic changes in microbes during...

2012-03-19 15:58:08

Mayo Clinic researchers have trained mouse immune systems to eradicate skin cancer from within, using a genetic combination of human DNA from melanoma cells and a cousin of the rabies virus. The strategy, called cancer immunotherapy, uses a genetically engineered version of the vesicular stomatitis virus to deliver a broad spectrum of genes derived from melanoma cancer cells directly into tumors. In early studies, 60 percent of tumor-burdened mice were cured in fewer than three months and...

2012-03-15 11:56:33

A salt-tolerant variety of durum wheat that outperforms other varieties by 25 per cent on salty soils has been developed by CSIRO scientists using traditional crop breeding techniques. Researchers have introduced a salt-tolerant gene into a commercial durum wheat which has produced spectacular results in field trials. "Salinity already affects more than 20 per cent of the world´s agricultural soils and is an increasing threat to food production due to climate change," CSIRO's Dr...

2012-03-12 09:55:40

A team of Australian scientists has bred salt tolerance into a variety of durum wheat that shows improved grain yield by 25% on salty soils. Using 'non-GM' crop breeding techniques, scientists from CSIRO Plant Industry have introduced a salt-tolerant gene into a commercial durum wheat, with spectacular results shown in field tests. Researchers at the University of Adelaide's Waite Research Institute have led the effort to understand how the gene delivers salinity tolerance to the plants....

2012-02-21 12:32:20

A team of researchers at Karolinska Institutet has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism behind putative side effects of the so-called PARP inhibitors, and can play an important role in the development of novel tailor-made cancer drugs. The study is presented in the journal Nature Biotechnology, and will hopefully contribute to new cancer therapies with fewer detrimental side effects....

2012-02-13 14:55:25

Study published in the journal Nature Biotechnology In a new study published online in Nature Biotechnology, researchers from BGI, the world's largest genomics organization, reported the evidence of extensive RNA editing in a human cell line by analysis of RNA-seq data, demonstrating the need for new robust methods to identify important post-transcriptional editing events. RNA editing is a normal but not yet fully understood process in which small nucleotide changes occur after DNA has...


Word of the Day
barratry
  • The offense of persistently instigating lawsuits, typically groundless ones.
  • An unlawful breach of duty on the part of a ship's master or crew resulting in injury to the ship's owner.
  • Sale or purchase of positions in church or state.
This word ultimately comes from the Old French word 'barater,' to cheat.
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