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Latest Nature Medicine Stories

2012-03-26 11:05:03

Finding may help develop new treatments for infectious diseases, cancer UCLA researchers pinpointed a new mechanism that potently activates T-cells, the group of white blood cells that play a major role in fighting infections. Published March 25 online in Nature Medicine, the team specifically studied how dendritic cells, immune cells located at the site of infection, become more specialized to fight the leprosy pathogen known as Mycobacterium leprae. Dendritic cells, like scouts in the...

2012-03-19 04:53:45

The discovery offers clues about how to turn on brain sensitivity to leptin and insulin, hormones that turn off appetite Researchers at Georgetown University Medical Center have revealed how a mutation in a single gene is responsible for the inability of neurons to effectively pass along appetite suppressing signals from the body to the right place in the brain. What results is obesity caused by a voracious appetite. Their study, published March 18th on Nature Medicine's website,...

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2012-03-13 08:48:17

In trying to unlock the potential of retinoids to treat patients with acute myeloid leukemia (AML), scientists have found the antidepressant called tranylcypromine (TCP) may be the key. Many types of AML can be treated with the retinoid all-trans retinoic acid (ATRA), a vitamin A-derivative. However, ATRA has not been shown to be effective with the more common types of AML. Arthur Zelent, PhD and his team at the Institute of Cancer Research (ICR) have been studying TCP to unlock the...

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2012-03-13 08:05:02

A group of researchers from Mount Sinai School of Medicine have identified a key regulator protein that plays a role in kidney fibrosis. Kidney fibrosis, or renal fibrosis, is a condition that ultimately leads to kidney failure. This research could be a potential relief for the millions of Americans affected by kidney failure. The Mount Sinai research team posted their findings in the March 11 issue of Nature Medicine. John Cijiang He, MD, PhD, Professor of Nephrology and Pharmacology...

2012-03-12 09:58:35

A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more common types of AMLs. Team leader Arthur Zelent, Ph.D., and colleagues at the ICR have been working to unlock the potential of retinoids to treat other patients with AML. In a paper published in Nature Medicine today, they show that the key could be an antidepressant...

2012-03-12 09:52:46

Researchers from Mount Sinai School of Medicine have identified a regulator protein that plays a crucial role in kidney fibrosis, a condition that leads to kidney failure. Finding this regulator provides a new therapeutic target for the millions of Americans affected by kidney failure. The research is published in the March 11 issue of Nature Medicine. Led by John Cijiang He, MD, PhD, Professor of Nephrology and Pharmacology and Systems Therapeutics; and Avi Ma'ayan, PhD, Assistant...

2012-03-08 01:00:52

Test likely to proceed to clinical trials In findings that may lead to clinical trials of a promising new drug for kidney disease, researchers at Beth Israel Deaconess Medical Center (BIDMC) and their colleagues have identified a key molecular player and shown how a targeted experimental drug can reverse kidney damage in mouse models of diabetes, high blood pressure, genetic kidney disease, and other kidney injuries. The study builds on a discovery that, in mice, a key protein can...

2012-02-27 07:24:19

Study in Nature Medicine could lead to novel therapy for cancer In a study published in Nature Medicine, Loyola researchers report on a promising new technique that potentially could turn immune system killer T cells into more effective weapons against infections and possibly cancer. The technique involves delivering DNA into the immune system's instructor cells. The DNA directs these cells to overproduce a specific protein that jumpstarts important killer T cells. These killer cells...

Study Could Result In Egg Cell Production For Fertility Treatments
2012-02-27 06:27:10

Researchers from Massachusetts General Hospital (MGH) have for the first time isolated stem cells that are capable of producing what appear to be normal egg cells or oocytes from the ovaries of reproductive age women. According to BBC News Health and Science Reporter James Gallagher, the research demonstrates that it could be possible to someday create a virtually unlimited supply of human eggs to assist with fertility treatments and help women hoping to have a child. Gallagher also...

2012-02-21 12:29:08

MD Anderson research shows promise for patients suffering from chronic pain By reformulating the common cancer drug imatinib (Gleevec®), researchers have eliminated morphine tolerance in rats — an important step toward improving the effectiveness of chronic pain management in patients, according to researchers at The University of Texas MD Anderson Cancer Center. Narcotics such as morphine are a mainstay of chronic pain treatment. Over time, tolerance to the pain-relieving...


Latest Nature Medicine Reference Libraries

Nature Medicine
2012-09-24 08:10:29

Nature Medicine is a peer-reviewed academic journal established in 1995 and published monthly by the Nature Publishing Group, a division of Macmillan Publishers Ltd. As with other Nature journals, this periodical has no external Editorial Board, with editorial decisions being made by an in-house team. Nature Medicine publishes research articles, reviews, news and commentary pieces. Topics include cancer, cardiovascular disease, gene therapy, immunology, vaccines, and neuroscience. Research...

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Word of the Day
mallemaroking
  • Nautical, the visiting and carousing of sailors in the Greenland ships.
This word is apparently from a confusion of two similar Dutch words: 'mallemerok,' a foolish woman, and 'mallemok,' a name for some persons among the crew of a whaling vessel.