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Last updated on April 16, 2014 at 17:34 EDT

Latest Netrin Stories

2011-01-19 14:09:55

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease"”early-onset familial Alzheimer's"”which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets. Without it, budding motor neurons misread their guidance signals and get...

2009-02-20 12:59:38

A study from the Buck Institute for Age Research offers a revolutionary new model for Alzheimer's disease (AD), a devastating neurodegenerative disorder which afflicts 24 million people worldwide. In an effort to unravel the normal function of a protein implicated in AD, scientists in California and France have discovered a naturally occurring protein that provides a new therapeutic target for the disease. The finding upsets the current theory that AD is a disease of toxicity stemming from...