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Latest Neural development Stories

2013-06-27 12:45:55

A new study helps explain how parts of the brain maintain their delicate balance of zinc, an element required in minute but crucial doses, particularly during embryonic development. The study, led at the Marine Biological Laboratory (MBL) by Mark Messerli in collaboration with scientists from the University of California, Davis, shows that neural cells require zinc uptake through a membrane transporter referred to as ZIP12.. If that route is closed, neuronal sprouting and growth are...

2013-06-25 10:59:01

Gene mutations that cause cell signaling networks to go awry during embryonic development and lead to major birth defects may also cause subtle disruptions in the brain that contribute to psychiatric disorders such as schizophrenia, autism, and bipolar disorder, according to new research by UC San Francisco scientists. Over the past several years, researchers in the laboratory of psychiatrist Benjamin Cheyette, MD, PhD, have shown that mice with mutations in a gene called Dact1 are born...

Stem Cells Down Syndrome Brain Development
2013-05-28 14:34:39

Brett Smith for redOrbit.com - Your Universe Online By reengineering skin cells from individuals with Down syndrome, scientists at the University of Wisconsin, Madison were able to learn how stem cells develop into dysfunctional brain cells when they contain an extra copy of chromosome 21, the genetic cause of the disorder. "Even though Down syndrome is very common, it's surprising how little we know about what goes wrong in the brain," said Anita Bhattacharyya, a stem cell researcher...

2013-05-09 11:22:27

A key type of human brain cell developed in the laboratory grows seamlessly when transplanted into the brains of mice, UC San Francisco researchers have discovered, raising hope that these cells might one day be used to treat people with Parkinson's disease, epilepsy, and possibly even Alzheimer's disease, as well as and complications of spinal cord injury such as chronic pain and spasticity. "We think this one type of cell may be useful in treating several types of neurodevelopmental and...

Early Differentiation Of Higher Brain Structures Affected By Competing Pathways
2013-04-26 11:36:30

Georgia Institute of Technology Sand-dwelling and rock-dwelling cichlids living in East Africa's Lake Malawi share a nearly identical genome, but have very different personalities. The territorial rock-dwellers live in communities where social interactions are important, while the sand-dwellers are itinerant and less aggressive. Those behavioral differences likely arise from a complex region of the brain known as the telencephalon, which governs communication, emotion, movement and...

2013-04-18 23:27:49

High-powered microscopes open a live look at a process where mutations lead to autism and other diseases Using spinning disk microscopy on barely day-old zebra fish embryos, University of Oregon scientists have gained a new window on how synapse-building components move to worksites in the central nervous system. What researchers captured in these see-through embryos -- in what may be one of the first views of early glutamate-driven synapse formation in a living vertebrate -- were...

2013-01-03 18:09:50

Research out of the George Washington University (GW), published in the journal Proceedings of the National Academy of Sciences (PNAS), reveals another piece of the puzzle in a genetic developmental disorder that causes behavioral diseases such as autism. Anthony-Samuel LaMantia, Ph.D., professor of pharmacology and physiology at the GW School of Medicine and Health Sciences (SMHS) and director of the GW Institute for Neuroscience, along with post-doctoral fellow Daniel Meechan, Ph.D. and...

2012-11-23 10:40:03

IRCM researchers discover a nerve cell´s internal clock A team of IRCM researchers, led by Dr. Frédéric Charron, recently uncovered a nerve cell´s internal clock, used during embryonic development. The discovery was made in collaboration with Dr. Alyson Fournier´s laboratory at the Montreal Neurological Institute. Published today in the prestigious scientific journal Neuron, this breakthrough could lead to the development of new tools to repair and...

2012-11-09 11:06:33

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have shown that a single protein plays an oversized role in intellectual and behavioral development. The scientists found that mutations in a single gene, which is known to cause intellectual disability and increase the risk of developing autism spectrum disorder, severely disrupts the organization of developing brain circuits during early childhood. This study helps explain how genetic mutations can cause profound...

2012-11-09 11:01:17

Neurodevelopmental disorders such as intellectual disability and autism spectrum disorders are marked by mutations that impair signaling between neurons. These mutations cause key brain circuits involved in learning and memory to develop too quickly, leading to long-lasting behavioral and cognitive deficits, according to a study published by Cell Press in the November 9th issue of the journal Cell. The findings could pave the way to new treatment strategies for severe forms of...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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