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Latest Neural development Stories

2012-03-23 09:51:57

Genetic studies find dysregulation in pathways that govern development of the prefrontal cortex in young patients with autism A study led by Eric Courchesne, PhD, director of the Autism Center of Excellence at the University of California, San Diego School of Medicine has, for the first time, identified in young autism patients genetic mechanisms involved in abnormal early brain development and overgrowth that occurs in the disorder. The findings suggest novel genetic and molecular targets...

2012-03-02 14:20:19

Upon fertilisation, a single cell is formed when egg and sperm fuse. Our entire body, with more than 200 specialised cell types and billions of cells are formed from this single cell. It is a scientific mystery how the early stem cells know what cell type to become, but a precise timing of the process is crucial for correct development and function of our body. Researchers across the world chase knowledge about our stem cells, as this knowledge holds great promises for development of...

2012-02-14 12:41:44

Researchers of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch have now identified and described a molecular mechanism underlying the most common malformation of the brain in humans. In holoprosencephaly (HPE), the forebrain (prosencephalon) is only incompletely formed. Here a binding site (receptor) for cholesterol plays a key role. If this receptor is defective, specific signals cannot be received, and the forebrain cannot separate into two hemispheres, as...

2012-02-13 11:09:37

Discovery provides clues to development of neurological diseases and cancer Researchers at the Salk Institute have discovered a startling feature of early brain development that helps to explain how complex neuron wiring patterns are programmed using just a handful of critical genes. The findings, published February 3 in Cell, may help scientists develop new therapies for neurological disorders, such as amyotrophic lateral sclerosis (ALS), and provide insight into certain cancers. The...

2012-02-10 11:34:53

A new study combines genetic and neurobiological approaches to confirm that synaptic mutations increase the risk of autism spectrum disorders (ASDs) A new study combines genetic and neurobiological approaches to confirm that synaptic mutations increase the risk of autism spectrum disorders (ASDs). It also highlights a role for modifier genes in these disorders. Published in PLoS Genetics, this research was conducted by researchers at the Institut Pasteur, the Paris Diderot University, the...

2012-01-25 12:24:06

From a new study in Biological Psychiatry A significant obstacle to progress in understanding psychiatric disorders is the difficulty in obtaining living brain tissue for study so that disease processes can be studied directly. Recent advances in basic cellular neuroscience now suggest that, for some purposes, cultured neural stem cells may be studied in order to research psychiatric disease mechanisms. But where can one obtain these cells outside of the brain? Increasingly,...

Cosmetic Chemical Hinders Brain Development In Tadpoles
2012-01-11 10:40:29

A new study finds that low concentrations of the chemical methylisothiazolinone has subtle but measurable negative effects on the neural development of tadpoles. The chemical is found in some cosmetics, although the study does not provide any evidence that cosmetics are unsafe for humans. Scientists, health officials, and manufacturers already know that a chemical preservative found in some products, including cosmetics, is harmful to people and animals in high concentrations, but a new...

2011-12-22 15:38:48

FINDINGS: Whitehead Institute scientists have identified conserved, long intervening non-coding RNAs (lincRNAs) that play key roles during brain development in zebrafish, and went on to show that the human versions of these RNAs can substitute for the zebrafish lincRNAs. RELEVANCE: Despite their prevalence in the cell, lincRNAs have been referred to as the "dark matter" of all the transcribed RNAs because little is known of their functions or mechanisms. Until now, lincRNAs have been...

2011-12-14 14:46:00

KIT Biologists Supply Major Results for Understanding the Thalamus, the “Relay Center” of the Brain The thalamus is the central translator in the brain: Specialized nerve cells (neurons) receive information from the sensory organs, process it, and transmit it deep into the brain. Researchers from the Institute of Toxicology and Genetics (ITG) of KIT have now identified the genetic factors Lhx2 and Lhx9 responsible for the development of these neurons. Their results contribute...

Researchers Turn Embryonic Stem Cells Into Functioning Neurons
2011-11-22 06:26:29

Scientists from the University of Wisconsin have successfully had implanted neurons, created in laboratory conditions, connect with the brains of mice and both send and receive signals. In research published Monday in the journal Proceedings of the National Academy of Sciences (PNAS), lead author Jason P. Weick and associates Yan Liu and Su-Chun Zhang describe how they were able to take blank slate human embryonic stem cells (hESC), turn them into neurons, implant them into the brains of...


Word of the Day
call-note
  • The call or cry of a bird or other animal to its mate or its young.
'Call-note' is newer than 'bird-call,' which originally referred to 'an instrument for imitating the note of birds' but now also refers to 'the song or cry of a bird.'
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