Quantcast

Latest Neuraminidase Stories

Genetic Defect Protects Mice From Infection With Influenza Viruses
2013-12-06 11:52:48

Helmholtz Centre for Infection Research A new study published in the scientific journal PLOS Pathogens points out that mice lacking a protein called Tmprss2 are no longer affected by certain flu viruses. The discovery was made by researchers from the Helmholtz Centre for Infection Research (HZI) in Braunschweig in collaboration with colleagues from Göttingen and Seattle. Whether it is H1N1, H5N1 or H7N9: The flu virus influenza A exists in many different types as its two coating...

2013-11-25 09:52:15

How a sugar-rich mucus barrier traps the virus -- and it gets free to infect Researchers at the University of California, San Diego School of Medicine have shown for the first time how influenza A viruses snip through a protective mucus net to both infect respiratory cells and later cut their way out to infect other cells. The findings, published online today in Virology Journal by principal investigator Pascal Gagneux, PhD, associate professor in the Department of Cellular and...

2013-09-24 09:40:36

Study may have implications for immunity against flu Scientists at Fred Hutchinson Cancer Research Center have uncovered a new mechanism by which influenza can infect cells – a finding that ultimately may have implications for immunity against the flu. Influenza viruses have two main proteins on their surface that allow them to do their dirty work: a protein called hemagglutinin allows viruses to infect cells, while a protein called neuraminidase allows viruses to escape from cells....

Scientists Develop Flu Drug Effective Against Drug-Resistant Virus
2013-02-23 09:29:00

Lee Rannals for redOrbit.com — Your Universe Online Scientists writing in the journal Science say they have found a new class of influenza drug is effective against drug-resistant strains of the flu virus. University of British Columbia (UBC) researchers published details about the development of a new drug candidate that is capable of preventing flu virus from spreading from one cell to the next. So far, the drug has tested successfully in mice trials, using lethal strains of the...

2012-01-18 12:58:11

Incomplete availability of data has hampered a thorough assessment of the evidence for using the anti-influenza drug oseltamivir, a Cochrane Review has found. However, after piecing together information from over 16,000 pages of clinical trial data and documents used in the process of licensing oseltamivir (Tamiflu) by national authorities, a team of researchers has raised critical questions about how well the drug works and about its reported safety profile. The new analysis shows...

2011-07-12 22:24:20

Findings could aid development of drugs exploiting flu protein "Ëœpockets' UC Irvine researchers have found a new approach to the creation of customized therapies for virulent flu strains that resist current antiviral drugs. Using powerful computer simulations, UCI's Rommie Amaro and Robin Bush created a method to predict how pocket structures on the surface of influenza proteins promoting viral replication can be identified as these proteins evolve, allowing for possible...

2011-01-12 14:44:05

Tom Jefferson and colleagues from the Cochrane Group argue that the current system for assessing the safety and effectiveness of drugs, based on published trial data only, is "wholly inadequate" and "ethically dubious." They propose a new approach that would allow in-depth scrutiny of the complete set of trial data for a new drug. Their call comes after they reviewed the evidence for the antiviral drug oseltamivir (Tamiflu), and were unable to find sufficient published data to support the...

2010-06-03 17:23:16

Biologists at the California Institute of Technology (Caltech) have pinpointed molecular changes that helped allow the global spread of resistance to the antiviral medication Tamiflu (oseltamivir) among strains of the seasonal H1N1 flu virus. The study"”led by David Baltimore, Caltech's Robert Andrews Millikan Professor of Biology and recipient of the 1975 Nobel Prize in Physiology or Medicine, and postdoctoral scholar Jesse D. Bloom"”appears in the June 4 issue of the journal...

2010-03-29 09:30:00

SAN DIEGO, March 29 /PRNewswire/ -- NexBio, Inc. announced today the publication in the Journal of Infectious Diseases of a preclinical study suggesting that treatment with DAS181 (Fludase®) may reduce the risk of secondary bacterial pneumonia following influenza virus infection. DAS181 is a broad spectrum host-targeted investigational drug candidate for treatment and prevention of Influenza-Like Illness (ILI) and has shown preclinical activity against numerous strains...

2010-02-26 09:15:23

A new study shows that a novel antiviral compound is effective against the highly pathogenic H5N1 avian influenza virus, including oseltamivir (Tamiflu)-resistant strains, according to scientists from Japan, Vietnam, Indonesia, and the University of Wisconsin-Madison. The research, published February 26 in the open-access journal PLoS Pathogens, suggests that the prodrug CS-8958 is a promising alternative antiviral for prevention and treatment of H5N1 influenza. Antiviral drugs are a primary...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.