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Latest Neurexin Stories

2010-10-08 02:27:38

New method helps explain synapse formation By creating a better way to see molecules at work in living brain cells, researchers affiliated with MIT's Picower Institute for Learning and Memory and the MIT Department of Chemistry are helping elucidate molecular mechanisms of synapse formation. These studies could also help further understanding of how synapses go awry in developmental diseases such as autism and Fragile X syndrome. The study will appear in the Oct. 7 issue of Cell. Using the...

2010-09-11 02:15:34

An international team of scientists, led by researchers at the University of California, San Diego, has identified misfolding and other molecular anomalies in a key brain protein associated with autism spectrum disorders. Palmer Taylor, associate vice chancellor for Health Sciences at UC San Diego and dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences, and colleagues report in the September 10 issue of the Journal of Biological Chemistry that misfolding of a protein called...

2009-10-12 14:41:21

A Stanford University School of Medicine researcher has pinpointed the mechanism by which a gene associated with both autism and schizophrenia influences behavior in mice. And just recently, he received a $1.65 million government grant to expand his efforts to include many more such genes. In a study to be published online on Oct. 12 in the Proceedings of the National Academy of Sciences, a team led by Thomas Sudhof, MD, the Avram Goldstein Professor in the School of Medicine and professor of...

2009-06-26 16:11:15

A gene variant that has been linked to alcohol and cocaine addiction may play a major role in obesity, U.S. and European researchers said. The researchers examined data from eight studies involving genes and body weight for more than 31,000 people ages 45 to 76. The researchers, who reported their findings PLoS Genetics, found those with a variant of the central-nervous system gene NRXN3 had a 10 percent to 15 percent higher risk of diabetes compared with those who didn't have it. NRXN3 is...

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2009-06-18 07:35:00

A protein called neuroligin that is implicated in some forms of autism is critical to the construction of a working synapse, locking neurons together like "molecular Velcro," a study lead by a team of UC Davis researchers has found. Published online in the June issue of the journal Neural Development, the study is accompanied by groundbreaking images that are the first to show two neurons coming together using neuroligin to construct a new synapse. "Previous research has suggested that...

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2008-11-18 09:25:18

Scientists have identified a relationship between two proteins in the brain that has links to both nicotine addiction and autism. The finding has led to speculation that existing drugs used to curb nicotine addiction might serve as the basis for potential therapies to alleviate the symptoms of autism. The discovery identified a defining role for a protein made by the neurexin-1 gene, which is located in brain cells and assists in connecting neurons as part of the brain's chemical...


Word of the Day
siliqua
  • A Roman unit of weight, 1⁄1728 of a pound.
  • A weight of four grains used in weighing gold and precious stones; a carat.
  • In anatomy, a formation suggesting a husk or pod.
  • The lowest unit in the Roman coinage, the twenty-fourth part of a solidus.
  • A coin of base silver of the Gothic and Lombard kings of Italy.
'Siliqua' comes from a Latin word meaning 'a pod.'
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