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Latest Neurobiology Stories

2012-06-25 02:26:56

ROCKVILLE, Md., June 25, 2012 /PRNewswire/ -- Neuralstem, Inc. (NYSE MKT: CUR) announced that the first patients were dosed in Phase Ib of its ongoing trial to test the safety of NSI-189 in the treatment of major depressive disorder (MDD). NSI-189, the lead compound in Neuralstem's small molecule platform, is a proprietary new chemical entity that stimulates new neuron growth in the hippocampus, a region of the brain believed to be implicated in MDD as well as other diseases and...

Nerve-less Sponge Has Clues To Nervous System Evolution
2012-06-18 15:25:18

UC Santa Barbara scientists turned to the simple sponge to find clues about the evolution of the complex nervous system and found that, but for a mechanism that coordinates the expression of genes that lead to the formation of neural synapses, sponges and the rest of the animal world may not be so distant after all. Their findings, titled "Functionalization of a protosynaptic gene expression network," are published in the Proceedings of the National Academy of Sciences. "If you're...

2012-06-06 10:35:12

A new study finds that the ear delivers sound information to the brain in a surprisingly organized fashion The brain receives information from the ear in a surprisingly orderly fashion, according to a University at Buffalo study scheduled to appear June 6 in the Journal of Neuroscience. The research focuses on a section of the brain called the cochlear nucleus, the first way-station in the brain for information coming from the ear. In particular, the study examined tiny biological...

2012-06-01 09:54:11

A protein produced by the central nervous system´s support cells seems to play two opposing roles in protecting nerve cells from damage, an animal study by Johns Hopkins researchers suggests: Decreasing its activity seems to trigger support cells to gear up their protective powers, but increasing its activity appears to be key to actually use those powers to defend cells from harm. Seth Blackshaw, Ph.D., an associate professor in the Solomon H. Snyder Department of Neuroscience at the...

2012-05-24 21:13:07

A molecule responsible for the proper formation of a key portion of the nervous system finds its way to the proper place not because it is actively recruited, but instead because it can't go anywhere else. Researchers at Baylor College of Medicine have identified a distal axonal cytoskeleton as the boundary that makes sure AnkyrinG clusters where it needs to so it can perform properly. "It has been known that AnkyrinG is needed for the axon initial segment to form. Without the axon...

2012-05-23 21:45:46

Researchers have shown in mice how immune cells in the brain target and remove unused connections between brain cells during normal development. This research, supported by the National Institutes of Health, sheds light on how brain activity influences brain development, and highlights the newly found importance of the immune system in how the brain is wired, as well as how the brain forms new connections throughout life in response to change. Disease-fighting cells in the brain, known as...

2012-05-21 02:25:59

ROCKVILLE, Md., May 21, 2012 /PRNewswire/ -- Neuralstem, Inc. (NYSE MKT: CUR) announced that Richard Garr, CEO and President, will present at the World Stem Cells & Regenerative Medicine Congress in London (http://www.terrapinn.com/2012/stemcells/index.stm) on Tuesday, May 22nd at 12:30 PM. Mr. Garr's presentation, "Stem Cell Applications for Neurodegenerative Disorders," will review Neuralstem's cellular therapy trial in ALS, its neurogenic small molecule trial in major depressive...

2012-04-11 22:16:57

A vast majority of cells in the brain are glial, yet our understanding of how they are generated, a process called gliogenesis, has remained enigmatic. Researchers at Baylor College of Medicine have identified a novel transcripitonal cascade that controls these formative stages of gliogenesis and answered the longstanding question of how glial cells are generated from neural stem cells. "Most people are familiar with neurons, cells that process and transmit information in the brain. Glial...

2012-03-29 22:24:42

A type of cell plentiful in the brain, long considered mainly the stuff that holds the brain together and oft-overlooked by scientists more interested in flashier cells known as neurons, wields more power in the brain than has been realized, according to new research published today in Science Signaling. Neuroscientists at the University of Rochester Medical Center report that astrocytes are crucial for creating the proper environment for our brains to work. The team found that the cells...

2012-03-15 05:39:01

(Ivanhoe Newswire)– Pill for spinal injury? A new study shows an oral drug that has shown promise in trials for human multiple sclerosis, significantly improves locomotor recovery in mice with spinal cord injury (SCI). Researchers uncover how a new pill that has shown positive results in mice with multiple sclerosis suffering from deterioration of the spinal cord, may help humans. Aside from the initial tissue damage, a great deal of the degradation of the spinal cord in SCI is...


Latest Neurobiology Reference Libraries

Brain
2013-03-05 13:54:00

Formation and Orientation The development of the brain is broken down into stages. The basic evolution begins in the third week of the embryonic process where the neural plate is formed. By week four, the neural plate has developed into the neural tube. The anterior part of the tube, the telencephalon, grows rapidly as it prepares to later give way to the brain. As time goes on, cells begin to classify themselves as either neurons or glial cells, thus determining their functions. Glial...

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