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Latest Neuroblastoma Stories

2010-04-20 07:30:00

NEW YORK, April 20 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) today announced that preclinical data in neuroblastoma for KRX-0401 (perifosine), the Company's novel, potentially first-in-class, oral anti-cancer agent that inhibits Akt activation in the phosphoinositide 3-kinase (PI3K) pathway, will be presented at the 101st Annual Meeting of the American Association for Cancer Research (AACR), currently being held in Washington, DC. The following poster will be...

2010-04-15 16:10:00

SUNNYVALE, Calif., April 15 /PRNewswire-FirstCall/ -- Pharmacyclics, Inc. (Nasdaq: PCYC) today announced multiple presentations covering its Btk and HDAC programs at the American Association for Cancer Research (AACR) 2010 Annual Meeting being held April 17-21 in Washington, DC. The oral presentation describes efficacy of the company's first-in-human Btk inhibitor PCI-32765 in a mouse model of pancreatic cancer (Soucek et al). Two other presentations describe the discovery of drug...

2010-03-01 12:30:00

New research in the FASEB Journal suggests that many types of childhood and adult cancers may be successfully treated with docosahexaenoic acid and its derivatives The next treatment for cancer might come from fish says a new research report published in the March 2010 print edition of the FASEB Journal (http://www.fasebj.org). In the report, scientists show that the omega-3 fatty acid, "docosahexaenoic acid" or "DHA," and its derivatives in the body kill neuroblastoma cancer cells. This...

2010-02-24 09:13:00

CHARLOTTE, N.C., Feb. 24 /PRNewswire-USNewswire/ -- Eight philanthropic organizations and families in the Charlotte region have joined forces to create the "Carolinas Kids Cancer Research Coalition," which is providing funding for the introduction of Phase I and Phase II clinical trials by the Pediatric Hematology and Oncology Center at Levine Children's Hospital (LCH). The coalition support includes a signature commitment of $1 million from the Alex Hemby Foundation and the Hemby family,...

2010-02-22 12:42:04

Researchers at the Sahlgrenska Academy at the University of Gothenburg, Sweden and Karolinska Institutet have used novel technology to reveal the different genetic patterns of neuroblastoma, an aggressive form of childhood cancer. This discovery may lead to significant advances in the treatment of this malignant disease, which mainly affects small children. The article is being published in the respected scientific journal, Proceedings of the National Academy of Sciences (PNAS). The study...

2010-02-16 08:46:36

A team of researchers, led by Patrick Mehlen, at Universit© de Lyon, France, has identified the protein NT-3 and the cell-surface molecule to which it binds (TrkC) as potential therapeutic targets for the treatment of neuroblastoma "” the most frequent solid tumor in young children"” by studying human neuroblastoma cells in vitro and after xenotransplantation into mice and chicks. In the study, NT-3 was found to be expressed at increased levels in aggressive human...

2009-12-09 10:41:22

Research: Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: Retrospective analysis of the Childhood Cancer Survivor Study cohort Children and adolescents who survive cancer have a significantly higher risk of developing heart disease as young adults, according to the largest study on this issue published on bmj.com today. The findings show that young adult survivors of childhood cancer are at risk for a variety of cardiovascular complications related to their...

2009-12-05 14:13:36

Late recurrence is a risk for some pediatric cancers, particularly Ewing sarcomas and tumors of the central nervous system, according to a new study published online December 4 in the Journal of the National Cancer Institute. This study was undertaken because there is limited research on late recurrence (after 5 years and up to 20 years) for pediatric cancer patients. Karen Wasilewski-Masker, M.D., of the Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta at...

2009-11-11 16:55:55

The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer Institute. In this study in mice, Tom Van Maerken, M.D., Center for Medical Genetics, Ghent University Hospital in Belgium, and colleagues evaluated the antitumor efficacy of nutlin-3, a potent and selective antagonist of the p53"“MDM2 interaction. Researchers found that...

2009-10-05 09:00:00

GURNEE, Ill., Oct. 5 /PRNewswire/ --This year you can wear your Halloween costume twice while helping kids with cancer. Hundreds of Chicagoans are expected to turn out in their favorite super hero costumes to raise money for pediatric cancer research at this year's Super Jake & Friends Heroes Bash on Saturday, Nov. 14 at the Northbrook Hilton in Northbrook, Ill., to benefit The Super Jake Foundation. "The five-year survival rate for neuroblastoma is only around 30 percent and...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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