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Last updated on April 17, 2014 at 17:30 EDT

Latest Neuroblastoma Stories

2009-12-09 10:41:22

Research: Cardiac outcomes in a cohort of adult survivors of childhood and adolescent cancer: Retrospective analysis of the Childhood Cancer Survivor Study cohort Children and adolescents who survive cancer have a significantly higher risk of developing heart disease as young adults, according to the largest study on this issue published on bmj.com today. The findings show that young adult survivors of childhood cancer are at risk for a variety of cardiovascular complications related to their...

2009-12-05 14:13:36

Late recurrence is a risk for some pediatric cancers, particularly Ewing sarcomas and tumors of the central nervous system, according to a new study published online December 4 in the Journal of the National Cancer Institute. This study was undertaken because there is limited research on late recurrence (after 5 years and up to 20 years) for pediatric cancer patients. Karen Wasilewski-Masker, M.D., of the Aflac Cancer Center and Blood Disorders Service, Children's Healthcare of Atlanta at...

2009-11-11 16:55:55

The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer Institute. In this study in mice, Tom Van Maerken, M.D., Center for Medical Genetics, Ghent University Hospital in Belgium, and colleagues evaluated the antitumor efficacy of nutlin-3, a potent and selective antagonist of the p53"“MDM2 interaction. Researchers found that...

2009-10-05 09:00:00

GURNEE, Ill., Oct. 5 /PRNewswire/ --This year you can wear your Halloween costume twice while helping kids with cancer. Hundreds of Chicagoans are expected to turn out in their favorite super hero costumes to raise money for pediatric cancer research at this year's Super Jake & Friends Heroes Bash on Saturday, Nov. 14 at the Northbrook Hilton in Northbrook, Ill., to benefit The Super Jake Foundation. "The five-year survival rate for neuroblastoma is only around 30 percent and...

2009-09-18 09:00:00

PHILADELPHIA, Sept. 18 /PRNewswire-USNewswire/ -- The Children's Hospital of Philadelphia announced the close of the Hope Lives Here fundraising campaign with a reception to honor Children's Hospital's most dedicated supporters. To celebrate the unbridled growth of Children's Hospital and the exemplary commitment of its philanthropic partners, Athena and Nicholas Karabots of Ft. Washington, Pennsylvania have graciously opened their home, Karamoor, to recognize the visionaries who helped...

2009-09-10 10:42:39

Why are some pediatric cancers able to spontaneously regress? Prof. Michael Fainzilber and his team of the Weizmann Institute's Biological Chemistry Department seem to have unexpectedly found part of the answer.  Further research towards a better understanding of the mechanism of action might hopefully lead, in the future, to the development of drugs that will be able to induce regression of certain tumors. TrkA is a particular cell receptor well known for its "pro-life...

2009-08-31 08:52:30

U.S. scientists studying Ewing's sarcoma -- a type of bone cancer -- have found high levels of a specific protein can suppress chemotherapy effects. Researchers at the University of Utah's Huntsman Cancer Institute discovered some patients with Ewing's sarcoma -- which typically afflicts children and young adults -- have poor outcomes if their tumors have high levels of a protein known as GSTM4. Our research shows that GSTM4 is found in high levels among those patients where chemotherapy...

2009-08-03 10:05:05

A new study published in the August issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) is an important tool for depicting the extent of neuroblastoma in some patients, particularly for those in the early stages of the disease. Neuroblastoma accounts for six to ten percent of all childhood cancers in the United States and 15 percent of cancer deaths in children. Accurately identifying where in the body the disease is located and whether it is spreading is...

2009-08-01 07:40:22

Survivors of the childhood cancer neuroblastoma are eight times more likely to have chronic health conditions, less likely to be married, and more likely to have lower incomes than their siblings, according to a study published online July 31 in the Journal of the National Cancer Institute. This study was undertaken because minimal information exists on the long-term outcomes for neuroblastoma survivors. Caroline Laverdiere, M.D., of the Sainte-Justine Hospital in Montreal, and colleagues...

2009-07-29 15:21:57

U.S. doctors conducted the first drug trial to help children with an often-fatal but little-understood cancer after identifying risk genes, the doctors say. The Children's Hospital of Philadelphia doctors say they hope to figure out what triggers neuroblastoma -- the most common cancer in infancy -- and why about half the cases are relatively benign and clear up on their own while the other half are more malignant. The doctors first scanned the DNA of hundreds of children with the disease and...