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Latest Neuroblastoma Stories

2012-05-09 21:35:10

Study is first to show feasibility and efficacy of a new use for autologous stem cell transplant For the first time, scientists at Fred Hutchinson Cancer Research Center have transplanted brain cancer patients' own gene-modified blood stem cells in order to protect their bone marrow against the toxic side effects of chemotherapy. Initial results of the ongoing, small clinical trial of three patients with glioblastoma showed that two patients survived longer than predicted if they had not...

2012-05-09 19:41:46

Ongoing research by a Baylor College of Medicine pediatric oncologist to understand how special cells called natural killer T (NKT) cells can be used to suppress neuroblastoma tumor growth has led to the discovery that the protein IL-15 is key to protecting the NKT cells' anti-tumor effectiveness in a hostile environment. The study, led by Dr. Leonid Metelitsa, associate professor of pediatrics — hematology/oncology at BCM and Texas Children's Cancer Center, appears in the current...

2012-04-13 05:28:27

(Ivanhoe Newswire) -- Around 80 percent of children with acute lymphoblastic leukemia (ALL) are now cured. With advancing treatment the cure rate may reach close to 90! Sounds promising right? According to a recent study, this figure is deceptive for children with unfavorable features defined by response to treatment or disease biology. In fact, some groups of children face a 50 percent cure rate. For example, a child with induction failure, where complete remission is not achieved after 4...

2012-03-14 11:49:00

St. Jude Children's Research Hospital — Washington University Pediatric Cancer Genome Project and Memorial Sloan-Kettering Cancer Center discover first gene alteration associated with patient age and neuroblastoma outcome Researchers have identified the first gene mutation associated with a chronic and often fatal form of neuroblastoma that typically strikes adolescents and young adults. The finding provides the first clue about the genetic basis of the long-recognized but poorly...

2012-03-13 22:34:15

Certain mutations of the gene ATRX were associated with age at diagnosis in children and young adults with advanced-stage neuroblastoma, a cancer that grows in parts of the nervous system, according to a study in the March 14 issue of JAMA. Neuroblastoma is the most common extracranial (outside the cranium) solid tumor of childhood and accounts for 15 percent of all cancer-related deaths in children. "Half of the patients (50 percent) with neuroblastoma present with metastatic disease;...

2012-03-12 20:35:30

A study by the Children's Oncology Group (COG) reported that five-year survival for acute lymphoblastic leukemia (ALL, the most common type of pediatric cancer) among children treated through COG clinical trials increased from 83.7 percent during the period 1990-1994 to 90.4 percent in the period 2000-2005. The improvements in survival were observed among all children over age 1 regardless of age, sex, ethnicity, or subtype of ALL. This analysis, which is the largest study to date of ALL...

2012-01-31 09:11:16

Results from a St. Jude Children's Research Hospital and the Children's Oncology Group study pinpoint genetic basis for increased leukemia risk facing Hispanic children and provide new hope for closing survival gap Hispanic children are more likely than those from other racial and ethnic backgrounds to be diagnosed with acute lymphoblastic leukemia (ALL) and are more likely to die of their disease. Work led by St. Jude Children's Research Hospital scientists has pinpointed genetic factors...

2011-12-13 12:14:03

A large, retrospective study shows that children of childhood cancer survivors who received prior treatment involving radiation to testes or ovaries and/or chemotherapy with alkylating agents do not have an increased risk for birth defects compared to children of survivors who did not have such cancer treatment. The findings provide reassurance that increased risks of birth defects are unlikely for cancer survivors who are concerned about the potential effects of their treatment on their...


Word of the Day
Cthulhu
  • A gigantic fictional humanoid alien god being described with a head resembling an octopus and dragon wings and claws, around whom an insane cult developed.
  • Pertaining to the mythos of Cthulhu and additional otherworldly beings created by H. P. Lovecraft or inspired by his writings and imitators.
This word was invented in 1926 by H.P. Lovecraft for his short story, 'The Call of Cthulhu.' 'Cthulhu' may be based on the word 'chthonic,' which in Greek mythology refers to the underworld.
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