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Latest Neurodegenerative disease Stories

2012-03-01 02:01:21

Promising avenue of neurodegenerative disease research may be a dead end In science, refuting a hypothesis can be as significant as proving one, all the more so in research aimed at elucidating how diseases proceed with a view toward preventing, treating, or curing them. Such a discovery can save scientists from spending precious years of effort exploring a dead end. In a study published in the Proceedings of the National Academy of Sciences, Munich-based researchers refute a widely...

2012-02-27 11:09:40

Millions of adults suffer from the incurable disease multiple sclerosis (MS). It is relatively certain that MS is an autoimmune disease in which the body's own defense cells attack the myelin in the brain and spinal cord. Myelin enwraps the nerve cells and is important for their function of transmitting stimuli as electrical signals. There are numerous unconfirmed hypotheses on the development of MS, one of which has now been refuted by the neuroimmunologists in their current research: The...

2012-02-22 21:34:08

Sometimes our immune defence attacks our own cells. When this happens in the brain we see neurodegenerative diseases such as dementia, Alzheimer´s and Parkinson´s disease. But if the the immune defence is inhibited, the results could be disastrous. Researchers at the University of Copenhagen have now discovered one of the molecular combat mechanisms in the brain that gets out of control in these diseases. In time this may enable targeted therapies to slow down the disease without...

2012-02-10 00:09:01

Findings Suggest New View of “Mad Cow” and Other Neurodegenerative Diseases Scientists from the Florida campus of The Scripps Research Institute have identified a single prion protein that causes neuronal death similar to that seen in “mad cow” disease, but is at least 10 times more lethal than larger prion species. This toxic single molecule or “monomer” challenges the prevailing concept that neuronal damage is linked to the toxicity of prion protein...

2012-02-01 11:34:15

Researchers from Mount Sinai School of Medicine have discovered that decaffeinated coffee may improve brain energy metabolism associated with type 2 diabetes. This brain dysfunction is a known risk factor for dementia and other neurodegenerative disorders like Alzheimer's disease. The research is published online in Nutritional Neuroscience. A research group led by Giulio Maria Pasinetti, MD, PhD, Professor of Neurology, and Psychiatry, at Mount Sinai School of Medicine, explored whether...

2012-01-25 08:00:00

DANA POINT, Calif., Jan. 25, 2012 /PRNewswire-USNewswire/ -- Rare Disease affects 350 million people worldwide, consisting of 7,000+ identified diseases and disorders. Currently less than 5% of all rare diseases have any type of therapy or treatment, and much of the early stage research is frequently seed-funded by parent advocates, advocacy organizations and non-profit groups. There is an important new trend in rare disease research where a group of rare disease advocates...

2012-01-17 22:47:27

A devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk has been traced to defects in mitochondria, the 'batteries' or energy-producing power plants of cells. This finding by a team of researchers, led by investigators from the Montreal Neurological Institute and Hospital — The Neuro- at McGill University, was published in this week's issue of the Proceedings of the National Academy of Sciences of the USA (PNAS). The research, which was...

2012-01-17 11:01:35

A devastating neurodegenerative disease that first appears in toddlers just as they are beginning to walk has been traced to defects in mitochondria, the 'batteries' or energy-producing power plants of cells. This finding by researchers at Queen Mary, University of London and Montreal Neurological Institute and Hospital - The Neuro - at McGill University, is published in this week's issue of the Proceedings of the National Academy of Sciences of the USA. The disorder, Autosomal...

2012-01-12 13:42:00

NEW YORK, Jan. 12, 2012 /PRNewswire-USNewswire/ -- The Alzheimer's Drug Discovery Foundation will host the 6th Annual Drug Discovery for Neurodegeneration Conference: An Intensive Course on Translating Research into Drugs on February 12-14, 2012, at the Princeton Club in New York City. The purpose of the conference is to educate scientists on the process of translating basic research into novel therapies, with a focus on Alzheimer's disease, Parkinson's disease, Amyotrophic Lateral Sclerosis...

2012-01-09 08:00:00

EAST SETAUKET, N.Y., Jan. 9, 2012 /PRNewswire/ -- Lixte Biotechnology Holdings (OTC: LIXT.PK) announces that the United States Patent and Trademark Office awarded a patent for the use of lead compounds from each of two different types of drugs, protein phosphatase inhibitors and histone deacetylase inhibitors, for the potential prevention and treatment of neurodegenerative diseases. Dr. John S. Kovach, founder and president of Lixte, said, "We have developed a series of novel...