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Latest Neurofibroma Stories

2014-04-04 08:24:48

Efforts lead to the launch of Neurofibromatosis (NF) MetaMiner PHILADELPHIA, April 4, 2014 /PRNewswire/ -- The Intellectual Property & Science business of Thomson Reuters, the world's leading provider of intelligent information for businesses and professionals, today announced an expansion of its partnership with the Children's Tumor Foundation (CTF) to create unique neurofibromatosis (NF) pathway maps aimed at significantly increasing the understanding of the disease and its...

2014-02-07 13:24:38

A genetic disorder that affects about 1 in every 2,500 births can cause a bewildering array of clinical problems, including brain tumors, impaired vision, learning disabilities, behavioral problems, heart defects and bone deformities. The symptoms and their severity vary among patients affected by this condition, known as neurofibromatosis type 1 (NF1). Now, researchers at Washington University School of Medicine in St. Louis have identified a patient’s gender as a clear and simple...

2013-12-27 10:33:27

A deadly, rare type of soft-tissue cancer may be completely eradicated simply by inhibiting a key protein involved in its growth, UT Southwestern Medical Center researchers report. In the study, published online today in Cell Reports, scientists found that inhibiting the action of a protein called BRD4 caused cancer cells to die in a mouse model of malignant peripheral nerve sheath tumors (MPNSTs). "This study identifies a potential new therapeutic target to combat MPNST, an incurable...

2013-10-03 16:11:47

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have identified a new drug candidate for an inherited form of cancer with no known cure. The new study showed the drug candidate—known as FRAX97—slowed the proliferation and progression of tumor cells in animal models of Neurofibromatosis type 2. This inherited type of cancer, caused by mutations in the anti-tumor gene NF2, leads to tumors of the auditory nerve that connects the inner ear to the brain. The...

2013-05-21 21:07:01

Researchers from the Masonic Cancer Center, University of Minnesota, and the University´s Brain Tumor Program, have developed a new mouse model of malignant peripheral nerve sheath tumors (MPNST) that allow them to discover new genes and gene pathways driving this type of cancer. The research was published this week in the journal Nature Genetics. Utilizing the Sleeping Beauty transposon method, researchers in the lab of David Largaespada, Ph.D., professor in the Medical School and...

Human Cancer Tumors Replicated In Mice And Then Cured
2013-03-06 09:23:12

April Flowers for redOrbit.com - Your Universe Online A group of scientists led by UT Southwestern Medical Center has reported the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer. "To my knowledge, this is the first time that a mouse model of a genetically defined malignant human cancer has been generated in which the formation of the tumor from beginning to end can be monitored and in which blocking the pathway cures the mouse of the...

2012-12-24 15:13:10

The causes of learning problems associated with an inherited brain tumor disorder are much more complex than scientists had anticipated, researchers at Washington University School of Medicine in St. Louis report. The disorder, neurofibromatosis 1 (NF1), is among the most common inherited pediatric brain cancer syndromes. Children born with NF1 can develop low-grade brain tumors, but their most common problems are learning and attention difficulties. “While one of our top...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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