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Latest Neurotoxicity Stories

2013-11-15 10:58:29

Identifying 'sensome' of microglia could improve understanding, treatments for neurodegenerative disorders Massachusetts General Hospital (MGH) investigators have used a new sequencing method to identify a group of genes used by the brain's immune cells – called microglia – to sense pathogenic organisms, toxins or damaged cells that require their response. Identifying these genes should lead to better understanding of the role of microglia both in normal brains and in neurodegenerative...

2012-11-29 12:37:32

Lanthanides comprise a unique and dominant resource of China. The increase in contact for populations through lanthanide mining and the wide applications for industry, agriculture, and medicine have raised great public concern regarding the metal toxicity of lanthanides, particularly on the issue of whether lanthanides are toxic to the human nervous system. In the past decade, major progresses have been made toward elucidating the mechanisms of the biological actions of lanthanides....

2009-08-05 13:23:01

The active ingredient in many insect repellents, N,N-Diethyl-3-methylbenzamide, known as DEET, may harm the central nervous system, French researchers said. Vincent Corbel from the Institut de Recherche pour le Developpement in Montpellier and Bruno Lapied of the University of Angers, both in France, led a team of researchers that investigated the toxicity of DEET. We've found that DEET is not simply a behavior-modifying chemical but also inhibits the activity of a key central nervous...

2008-07-24 12:01:22

Sound Pharmaceuticals has filed an investigational new drug application with the FDA for the clinical testing of a proprietary formulation of ebselen for the prevention of chemotherapy induced hearing loss or ototoxicity. The oral capsule containing ebselen, SPI-3005, will be tested in advanced stage lung cancer and head and neck cancer patients receiving platinum based chemotherapy. This marks the second development program for SPI to enter clinical testing for a hearing loss...

2005-06-08 17:59:26

ROCHESTER, Minn. - A Mayo Clinic case series analysis has pinpointed for the first time syndromes associated with toxic damage to the brain and nervous system from manganese fumes generated during welding. The analysis also revealed that all affected patients shared a risk factor: welding with inadequate ventilation. The findings are published online at www.neurology.org and will appear in the June 28 print issue of Neurology. Due to ethical concerns, human trials with manganese fume...


Word of the Day
cacodemon
  • An evil spirit; a devil.
  • A nightmare.
  • In astrology, the twelfth house of a scheme or figure of the heavens: so called from its signifying dreadful things, such as secret enemies, great losses, imprisonment, etc.
'Cacodemon' comes from a Greek term meaning 'evil genius.'
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