Quantcast

Latest Neurotransmitter transporters Stories

2014-07-24 11:40:21

UCI News Flawed dopamine signaling linked to mass alteration of gene activity in prefrontal cortex Dysfunction in dopamine signaling profoundly changes the activity level of about 2,000 genes in the brain’s prefrontal cortex and may be an underlying cause of certain complex neuropsychiatric disorders, such as schizophrenia, according to UC Irvine scientists. This epigenetic alteration of gene activity in brain cells that receive this neurotransmitter showed for the first time that...

2014-07-03 12:51:53

University of Copenhagen Researchers at the University of Copenhagen and the Copenhagen University Hospital have identified a particular genetic mutation that may cause parkinsonism in young people. The mutation interferes with the brain's transport of the important signal substance dopamine and may also plays a role in mental diseases, e.g. ADHD. The findings have just been published in the scientific Journal of Clinical Investigation. Being one of the most important signal substances...

2014-06-11 08:28:27

DATA FROM KINECT 1 AND KINECT 2 TARDIVE DYSKINESIA STUDIES SAN DIEGO, June 11, 2014 /PRNewswire/ -- Neurocrine Biosciences, Inc. (NASDAQ:NBIX) today announced that on June 11, 2014, two scientific posters associated with its study of NBI-98854 in Phase IIb clinical trials of tardive dyskinesia patients, will be presented at the 2014 Annual Congress of Parkinson's Disease and Movement Disorders in Stockholm Sweden. This annual meeting brings together over 5,000 clinicians and...

Depression May Be Detectable By A Blood Test
2014-04-30 07:21:24

April Flowers for redOrbit.com - Your Universe Online Typically, diagnosing depression involves discussions about symptoms with a doctor or a therapist. It isn't an exact science, because until now, there wasn't an empirical test for most mental illnesses. A new study from the Medical University of Vienna (MedUni Vienna) might just change that. The study findings, published in PLOS ONE, demonstrate that in principle it might be possible to use a blood test to detect depression. The...

2012-10-26 00:35:45

Scientists may have discovered why the standard treatment for Parkinson's disease is often effective for only a limited period of time. Their research could lead to a better understanding of many brain disorders, from drug addiction to depression, that share certain signaling molecules involved in modulating brain activity. A team led by Bernardo Sabatini, Takeda Professor of Neurobiology at Harvard Medical School, used mouse models to study dopamine neurons in the striatum, a region of...

Glowing Molecules Help Scientists Track Serotonin
2012-07-02 10:08:10

[ Watch the Video ] John Neumann for redOrbit.com - Your Universe Online Researchers have succeeded in tracking a single protein that regulates the neurotransmitter serotonin, making it possible to study the dynamics of the protein which regulates mood, appetite and sleep, at an unprecedented level of detail, reports David Salisbury of Vanderbilt University. Attempts to understand how these transporters work have been limited by the difficulty of studying their dynamic behavior. The...

2012-03-20 16:56:28

Early disruptions in serotonin signaling in the brain may contribute to autism spectrum disorder (ASD), and other "enduring effects on behavior," Vanderbilt University researchers report. Serotonin is a brain chemical that carries signals across the synapse, or gap between nerve cells. The supply of serotonin is regulated by the serotonin transporter (SERT). In 2005, a team of Vanderbilt researchers led by Randy Blakely and James Sutcliffe identified rare genetic variations in children...

2011-10-03 13:22:38

New approach simplifies the search for more specific drugs Psychiatric ailments such as depression, obsessive-compulsive disorder or anxiety states are often associated with disturbances in the metabolism of the neurotransmitter serotonin. Neurotransmitters are compounds that are released from the synapses at nerve cell endings and activate the firing of neighboring neurons. Thus, as their name suggests, they mediate the transmission of nerve impulses. The serotonin transporter (SERT) is...

2011-04-25 13:48:15

New discoveries may lead to insights into drug abuse and depression A team of scientists from Columbia University College of Physicians and Surgeons and Weill Cornell Medical College has shed light on the molecular workings of transporter proteins, molecular machines embedded in the cell membranes of neurons that modulate the transfer of signals between cells and recycle neurotransmitters. The research, published today in the journal Nature, reveals with unprecedented detail how the molecule...


Word of the Day
vermicular
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.
Related