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Last updated on April 19, 2014 at 5:20 EDT

Latest Neurotrophins Stories

2014-03-26 16:08:03

Decreased exposure to air pollution associated with increases in key protein in brain development Decreased exposure to air pollution in utero is linked with improved childhood developmental scores and higher levels of brain-derived neurotrophic factor (BDNF), a key protein for brain development, according to a study looking at the closure of a coal-burning power plant in China led by researchers at the Columbia Center for Children's Environmental Health at the Mailman School of Public...

One Gene Influences Traumatic Brain Injury Recovery
2014-02-27 15:29:46

University of Illinois at Urbana-Champaign Researchers report that one change in the sequence of the BDNF gene causes some people to be more impaired by traumatic brain injury (TBI) than others with comparable wounds. The study, described in the journal PLOS ONE, measured general intelligence in a group of 156 Vietnam War veterans who suffered penetrating head wounds during the war. All of the study subjects had damage to the prefrontal cortex, a brain region behind the forehead that is...

Neuroscience Study Reveals New Player In Obesity
2014-01-08 08:24:33

Tufts University, Health Sciences Campus A protein directs appetite suppressor in the brain; implications for obesity treatment A new neuroscience study sheds light on the biological underpinnings of obesity. The in vivo study, published in the January 8 issue of the Journal of Neuroscience, reveals how a protein in the brain helps regulate food intake and body weight. The findings reveal a potential new avenue for the treatment of obesity and may help explain why medications that are...

Researchers Uncover Mechanism For Improving Song Learning In Young Zebra Finches
2013-10-23 12:49:50

Max Planck Institute Most songbirds learn their songs from an adult model, mostly from the father. However, there are relatively large differences in the accuracy how these songs are copied. Researchers from the Max Planck Institute for Ornithology in Seewiesen now found in juvenile zebra finches a possible mechanism that is responsible for the differences in the intensity of song learning. They provided the nerve growth factor “BDNF” to the song control system in the brain. With this...

2013-03-13 08:30:50

SAN DIEGO, March 13, 2013 /PRNewswire/ -- Ceregene, Inc. today announced the completion of enrollment in its double-blind Phase 2 clinical study of CERE-110 (AAV-NGF), a gene therapy product designed to deliver nerve growth factor (NGF) for the treatment of Alzheimer's disease. The clinical study was carried out in collaboration with the Alzheimer's Disease Cooperative Study (ADCS) based at the University of California San Diego (UCSD) and funded by a grant from the National Institute on...

2012-12-06 15:28:02

The study, led by an OHSU School of Dentistry researcher, is the first to link blood pressure with levels of a molecule known as BDNF, or Brain-Derived Neurotrophic Factor Researchers at Oregon Health & Science University's School of Dentistry have made an important connection between a molecule critical to nerve cells and high blood pressure. Production of the molecule Brain-Derived Neurotrophic Factor (BDNF) appears to increase dramatically in blood pressure-sensing nerve cells...

2012-10-30 12:35:05

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases. In Lou Gehrig's Disease (ALS) and other neurodegenerative diseases, nerve cells usually die in stages, with axons deteriorating first and the cells themselves perishing later. Axon degeneration may represent a...

2012-10-11 13:05:50

Repairing brain damage a significant departure from current treatments Washington State University researchers have developed a new drug candidate that dramatically improves the cognitive function of rats with Alzheimer's-like mental impairment. Their compound, which is intended to repair brain damage that has already occurred, is a significant departure from current Alzheimer's treatments, which either slow the process of cell death or inhibit cholinesterase, an enzyme believed to...

2012-10-09 10:52:41

Deletion of brain-derived neurotrophic factor leads to major depression, anxiety, and obesity McGill researchers have identified a small region in the genome that conclusively plays a role in the development of psychiatric disease and obesity. The key lies in the genomic deletion of brain-derived neurotrophic factor, or BDNF, a nervous system growth factor that plays a critical role in brain development. To determine the role of BDNF in humans, Prof. Carl Ernst, from McGill's Department...

Semen Protein Prompts Ovulation
2012-08-21 09:17:20

John Neumann for redOrbit.com - Your Universe Online A brave team of researchers led by Canadian Gregg Adams from the University of Saskatchewan have discovered a protein in semen that acts on the brains of females prompting ovulation, and is the same molecule that regulates the growth, maintenance, and survival of nerve cells, reports e! Science News. The international team of researchers found that male mammals have accessory sex glands that contribute seminal fluid to semen, but the...