Quantcast

Latest Neutralizing antibody Stories

2011-10-07 11:02:55

A researcher at MIT's Koch Institute for Integrative Cancer research has identified a gene that controls the process by which antibodies gain their ability to combat retroviruses. Edward Browne shows that the gene TLR7 allows the antibody generating B cells to detect the presence of a retrovirus and promotes a process by which antibodies gain strength and potency, called a germinal center reaction. The findings are published in the Open Access journal PLoS Pathogens on October 6th. TLR7 is...

2011-09-12 05:14:30

By Alicia Rose DelGallo, Ivanhoe Health Correspondent (Ivanhoe Newswire) -- The pandemic still rages as 33.4 million people worldwide live with the human immunodeficiency virus (HIV). Currently no vaccine exists that effectively prevents HIV. However, new improvements, published today by Maraget I. Johnston, Ph.D., and Anthony S. Fauci, M.D., in the New England Journal of Medicine, are taking HIV vaccine development down an innovative path. Typically, the best way to develop an...

2011-09-08 11:33:11

New Advances Provide Reason for Optimism The human body can produce powerful antibodies that shield cells in the laboratory against infection by an array of HIV strains. In people, however, recent research shows that these broadly neutralizing antibodies are not produced in an efficient or timely enough fashion in HIV-infected individuals to effectively block progression of infection, appearing only after a person has been infected with HIV for at least one year -- by which time the virus...

2011-09-02 11:42:22

Researchers at Duke University Medical Center, Beth Israel Deaconess Medical Center and Harvard Medical School have demonstrated an approach to HIV vaccine design that uses an altered form of HIV's outer coating or envelope protein. The researchers showed that they could design HIV envelopes that could bind better to immature B cell receptors to create an enhanced immune response in an animal model. Immature B cells are the targets of vaccines, and when strongly targeted, they produce...

2011-05-23 14:29:42

The HIV epidemic is the largest in the world and represents one of the most serious public health problems, according to data from the World Health Organization (WHO). Only 30% of the more than 10 million patients in need have the access to the antiretroviral treatment. The total number of infected people exceeds 30 million and there are about 3 million new infections per year. The best hope for reducing the incidence of AIDS (Acquired Immune Deficiency Syndrome) is a preventive vaccine. The...

2011-02-10 19:34:52

New research shows that protective immunity against HIV can be achieved without the presence of virus neutralizing antibodies in the blood New research shows that protective immunity against HIV can be achieved without the presence of virus neutralizing antibodies in the blood. The study, published by Cell Press in the February issue of the journal Immunity, demonstrates that a vaccine which stimulates production of specific anti-HIV antibodies in the vaginal tissue was sufficient to protect...

2011-01-14 08:57:23

New findings are bringing scientists closer to an effective HIV vaccine. Researchers from Seattle Biomedical Research Institute (Seattle BioMed), Vanderbilt University and the Ragon Institute of MGH, MIT and Harvard report findings showing new evidence about broadly-reactive neutralizing antibodies, which block HIV infection. Details are published January 13 in the open-access journal PLoS Pathogens. According to author Leo Stamatatos, Ph.D., director of the Viral Vaccines Program at Seattle...

2010-11-19 12:14:47

Researchers have been stymied for years over the fact that people infected with the AIDS virus do indeed produce antibodies in response to the pathogen "“ antibodies that turn out to be ineffective in blocking infection. Now, scientists at Duke University Medical Center can explain why: Some of the earliest and most abundant antibodies available to fight HIV can't actually "see" the virus until after it's already invaded a healthy cell. The scientists based their conclusion on the...

2010-09-30 14:40:27

New discoveries about the immune defenses of rare HIV patients who produce antibodies that prevent infection suggest a novel direction for designing new vaccines. Researchers at Rockefeller University and colleagues have now made two fundamental discoveries about the so called broadly neutralizing anti-HIV antibodies, which effectively keep the virus at bay. By detailing the molecular workings of a proven immune response, the researchers hope their work will ultimately enable them to...


Word of the Day
lambent
  • Licking.
  • Hence Running along or over a surface, as if in the act of licking; flowing over or along; lapping or bathing; softly bright; gleaming.
This word comes the Latin 'lambere,' to lick.
Related