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Latest Neutralizing antibody Stories

2010-09-29 09:17:49

(Ivanhoe Newswire) "“ There are 31.1 million adults and 2.1 million children living with HIV in the world.  There is no cure for the disease. But what if there was a vaccine that could be administered to everyone to stop the spread of HIV? The HIV/AIDS epidemic would be over. One way to produce an HIV vaccination is to teach the immune system to recognize certain protein structures on the surface of the HIV virus and produce antibodies that will bind to the structures and...

2010-08-02 20:53:02

Monkeys repeatedly immunized with a particular form the HIV-1 envelope glycoprotein generated antibodies capable of neutralizing diverse strains of HIV-1, according to a paper published online in the Journal of Experimental Medicine on August 2. Antibodies in the blood of monkeys immunized with a HIV-1 envelope trimer neutralized a broader variety of HIV-1 strains than antibodies in the blood of humans immunized with an HIV-1 envelope monomer during the VAX04 phase III clinical trial....

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2010-07-09 10:53:44

Discovery to advance HIV vaccine design, antibody therapy for other diseases Scientists have discovered two potent human antibodies that can stop more than 90 percent of known global HIV strains from infecting human cells in the laboratory, and have demonstrated how one of these disease-fighting proteins accomplishes this feat. According to the scientists, these antibodies could be used to design improved HIV vaccines, or could be further developed to prevent or treat HIV infection. Moreover,...

2010-06-02 13:43:02

The findings advance the effort to develop an AIDS vaccine In findings that contribute to efforts to design an AIDS vaccine, a team led by Scripps Research Institute scientists has determined the structure of an immune system antibody molecule that effectively acts against most strains of human immunodeficiency virus (HIV), the virus that causes AIDS. The study, which is being published in an advance, online issue of the journal Proceedings of the National Academy of Sciences (PNAS) during...

2009-12-15 23:38:21

Scientists seeking to understand how to make an AIDS vaccine have found the cause of a major roadblock. It turns out that the immune system can indeed produce cells with the potential to manufacture powerful HIV-blocking antibodies "“ but at the same time, the immune system works equally hard to make sure these cells are eliminated before they have a chance to mature. "These studies show that a potentially protective neutralizing antibody against a viral disease is under the control of...

2009-11-20 12:43:27

WHAT: New discoveries about anti-HIV antibodies may bring researchers a step closer to creating an effective HIV vaccine, according to a new paper co-authored by scientists at the Vaccine Research Center of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health. Scientists know that an HIV-neutralizing antibody called b12 binds to gp120, an HIV surface protein, at one of the few areas of the virus that does not mutate: the site where gp120...

2009-11-09 15:32:16

A very close and detailed study of how the most robust antibodies work to block the HIV virus as it seeks entry into healthy cells has revealed a new direction for researchers hoping to design an effective vaccine. "Our study clearly showed that we've been overlooking a very important component of antibody function," says S. Munir Alam, Ph.D., an associate professor of medicine at Duke University Medical Center and lead author of the paper appearing in the Proceedings of the National Academy...

2009-09-21 14:37:38

Scientists working to develop a vaccine for the human immunodeficiency virus (HIV) report they have created the first antigen that induces protective antibodies capable of blocking infection of human cells by genetically-diverse strains of HIV. The new antigen differs from previously-tested vaccines by virtue of its chemically-activated property that enables close sharing of electrons and produces strong covalent bonding. Researchers used a mouse model to generate the antibodies. The report...

2009-09-19 10:20:52

A study of how HIV mutates in response to immune system pressure by Emory Vaccine Center researchers shows that the virus can take several escape routes, not one preferred route. The results are online and scheduled for publication in the September issue of the journal Public Library of Science Pathogens. The human immune system has the ability to temporarily overpower HIV in early infection. Recent research has shown that most newly infected patients develop neutralizing antibodies. These...

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2009-09-03 13:50:00

Findings reveal an Achilles heel on the virus for AIDS vaccine researchers to exploit Researchers at and associated with the International AIDS Vaccine Initiative (IAVI), at The Scripps Research Institute, and at the biotechnology companies Theraclone Sciences and Monogram Biosciences have discovered two powerful new antibodies to HIV that reveal what may be an Achilles heel on the virus. They published their work in Science this week. Researchers will now try to exploit the newfound...


Word of the Day
glogg
  • Scandinavian punch made of claret and aquavit with spices and raisins and orange peel and sugar.
This word comes from the Swedish 'glogg,' which is an alteration of 'glodgat,' mulled (wine).
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