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Latest Neutrophil granulocyte Stories

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2009-09-08 09:35:00

Insects could replace many lab mice used for evaluating the safety of certain drugs, researchers reported on Tuesday. Dr. Kevin Kavanagh, from the National University of Ireland, and colleagues found that insects, such as moths, and fruit flies, could safely be used to replace mice in lab testing for drug safety. Kavanagh presented his findings to the Society for General Microbiology's meeting at Heriot Watt University, Edinburgh on Tuesday. The team showed that neutrophils "“ a type of...

2009-03-16 13:18:30

U.S. medical scientists say they have discovered a new method to prevent bacterial infections by using the body's own enzymes. Dr Quinn Parks and colleagues at Denver's National Jewish Health Hospital said they used enzymes against products of the body's own defense cells to prevent Pseudomonas aeruginosa bacteria from building a protective biofilm that enables the bacteria to avoid both the body's immune mechanisms and antibiotics. When the body's defense cells, called neutrophils, attack P....

2009-02-25 11:35:28

Researchers have found a way to block the ability of white blood cells to sprint toward the sites of infection when such speed worsens the damage done by sepsis, the often fatal, whole-body bacterial infection, according to a study published today in the journal Blood. The results recommend existing drugs as potential new treatments against sepsis, and suggest improvements in the current treatment that would increase its effect while eliminating a treatment-related risk for internal...

2009-01-02 15:13:10

A team of scientists has discovered a new syndrome associated with severe congenital neutropenia (SCN), a rare disorder in which children lack sufficient infection-fighting white cells, and identified the genetic cause of the syndrome: mutations in the gene Glucose-6-phosphatase, catalytic subunit 3 (G6PC3). The findings, which are published in the Jan. 1, 2009 issue of The New England Journal of Medicine, were made by an international team of scientists, composed of 14 researchers from the...

2008-12-23 06:00:00

SOPHIA ANTIPOLIS, France, December 23 /PRNewswire-FirstCall/ -- NicOx S.A. (NYSE Euronext Paris: COX) today announced the results of a phase 2a study for TPI 1020, conducted in 62 patients with Chronic Obstructive Pulmonary Disease (COPD) by its partner Topigen Pharmaceuticals Inc. TPI 1020 showed good overall safety and tolerability, although its activity profile was not significantly different from budesonide, a conventional corticosteroid commonly used in respiratory disorders. TPI...

2008-09-02 03:00:12

By Anonymous In the June issue of Circulation (2008;117:2901-2911), Belun et al. from the Oregon Health and Science University (Portland) reported on a study using ultrasound perfusion imaging and molecular imaging with microbubbles to assess inflammatory cell recruitment and endothelial cell activation during vasculogenesis and ischemia- mediated arteriogenesis. The study was conducted in wild-type or monocyte chemotaclic protein-1-deficient mouse models of vasculogenesis (subcutaneous...

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2008-08-13 15:50:00

"Flesh-eating" or "Strep" bacteria are able to survive and spread in the body by degrading a key immune defense molecule, according to researchers at the University of California, San Diego, School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences. The finding, which could aid in development of new treatments for serious infections in human patients, will be reported in the August 14 issue of the journal Cell Host & Microbe. Led by senior author Victor Nizet, M.D., UC...

2008-07-01 12:00:15

U.S. medical scientists say they've made a discovery that might lead to a new therapeutic target for acute respiratory distress syndrome, or ARDS. In ARDS, the lungs become swollen with water and protein, and breathing becomes impossible, leading to death in 30 percent to 40 percent of cases. There is no effective treatment. University of Illinois-Chicago researchers said it has previously been shown an enzyme called non-muscle myosin light-chain kinase, or MYLK, plays a pivotal role in...

2008-07-01 09:00:12

U.S. researchers make promising finding in severe lung disease WASHINGTON, June 30 (Xinhua) -- Researchers at University of Illinois have identified a novel function for an enzyme that plays a role in the tissue injury in acute respiratory distress syndrome, also known as ARDS, according to the latest online version of the journal Nature Immunology. The finding offers a completely new set of possible therapeutic targets for the prevention and treatment of lung inflammation and injury....

2005-09-06 18:10:00

GAINESVILLE, Fla. - University of Florida researchers have uncovered how the inhaled form of anthrax disarms bacteria-fighting white blood cells before they can fend off the disease, which kills most victims within days. The lethal toxin in anthrax paralyzes neutrophils, the white blood cells that act as the body's first defense against infection, by impairing how they build tiny filaments that allow them to crawl throughout the body and eat invading bacteria. Just two hours of exposure to...


Word of the Day
mundungus
  • A stinking tobacco.
  • Offal; waste animal product; organic matter unfit for consumption.
This word comes from the Spanish 'mondongo,' tripe, entrails.