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Latest New England Journal Stories

2012-09-10 10:58:02

Study drives home importance of addressing unique needs in specific patient populations Although some studies have portrayed tight blood sugar control as a potential means of lowering infection rates in critically ill adults, a new study–led by principal investigator Michael Agus, MD, director of the Medicine Critical Care Program at Boston Children's Hospital–found no indication that the approach benefits pediatric patients undergoing heart surgery. The results of the Safe...

2012-09-06 12:48:22

Provocative NEJM essay calls for redoubling of efforts Each year, nearly 2 million people die from tuberculosis — a treatable disease that has been brought under control in the United States, but continues to ravage other parts of the world. This health inequity should prompt a complete rethinking of the way tuberculosis is fought on a global level, argue Salmaan Keshavjee, MD, PhD, and Paul Farmer, MD, PhD, from Brigham and Women's Hospital (BWH). Their argument appears in an essay...

2012-08-30 10:24:03

NIH study also shows that overall stroke risk is down from 10 years ago Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health. Lacunar strokes occur due to chronic high blood pressure and typically produce small lesions deep within the brain....

2012-08-28 12:06:03

For patients with stable coronary artery disease who have at least one narrowed blood vessel that compromises flow to the heart, medical therapy alone leads to a significantly higher risk of hospitalization and the urgent need for a coronary stent when compared with therapy that also includes initial placement of artery-opening stents. Those are the findings of a study to be published online Aug. 28 in the New England Journal of Medicine that was designed to evaluate the benefits of using...

2012-08-27 11:48:32

Potential long-term benefit observed for first time in ACS patients The first trial to study patients with acute coronary syndrome who do not undergo coronary stenting or bypass surgery found no significant difference between two anti-clotting drugs — prasugrel and clopidogrel — in preventing the first occurrence of death, heart attack or stroke, according to Duke University Medical Center cardiologists. The study also showed no difference in serious bleeding complications....

2012-08-23 10:56:29

Autoantibody may cause susceptibility to opportunistic infections A clinical study led by National Institutes of Health investigators has identified an antibody that compromises the immune systems of HIV-negative people, making them susceptible to infections with opportunistic microbes such as nontuberculous mycobacteria (NTM). In this study conducted at hospitals in Thailand and Taiwan, the researchers found that the majority of study participants with opportunistic infections made an...

2012-08-16 13:08:51

Oral drug shows clinical response and remission in some patients An investigational drug currently under FDA review for the treatment of rheumatoid arthritis has now shown positive results in patients with moderate-to-severe ulcerative colitis, according to researchers at the University of California San Diego, School of Medicine. The study will appear in the August 16, 2012 issue of the New England Journal of Medicine (NEJM). Results from the phase 2 clinical trial showed the drug...

2012-08-03 01:04:45

In a Perspective article appearing in this week's New England Journal of Medicine, public health researchers examine how recommendations in a new report from the Institute of Medicine (IOM)–"Accelerating Progress in Obesity Prevention: Solving the Weight of the Nation"–square with American's opinions about the obesity epidemic. Over the last 30 years, rates of obesity have doubled among adults and tripled among children. The new IOM report summarizes growing evidence that these...

2012-08-02 22:21:21

New treatment option extends median survival time by more than 6 months Postmenopausal women with the most common type of metastatic breast cancer now have a new treatment option that lengthens their lives, according a study led by UC Irvine oncologist Dr. Rita Mehta and conducted by the Southwest Oncology Group. The findings appear in the Aug. 2 issue of the New England Journal of Medicine. A combination of the two anti-estrogen drugs anastrozole and fulvestrant extended the median...


Word of the Day
malpais
  • The ragged surface of a lava-flow.
'Malpais' translates from Spanish as 'bad land.'