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Latest New England Journal Stories

2013-03-28 10:47:28

Interaction between gene and environment predicts disease onset About 90 percent of children with two copies of a common genetic variation and who wheezed when they caught a cold early in life went on to develop asthma by age 6, according to a study to be published March 28 by the New England Journal of Medicine. These children, all from families with a history of asthma or allergies, were nearly four times as likely to develop the disease as those who lacked the genetic variation and...

2013-03-22 15:22:38

Population at high risk for obesity-related mortality able to make healthy lifestyle changes Through a program that teaches simple nutrition messages and involves both counseling and regular exercise classes, people with serious mental illness can make healthy behavioral changes and achieve significant weight loss, according to new Johns Hopkins research. These weight loss amounts were similar to those in other successful programs studied with subjects in the general population –...

2013-03-21 10:12:50

Long-term follow-up of a phase II study from KEMRI-Wellcome Trust Research Programme and Oxford University researchers in Kenya shows that the efficacy of a malaria vaccine candidate, RTS,S, wanes over time and varies with exposure to the malaria parasite. The findings will help to inform which populations are likely to benefit most from the vaccine candidate. They also have important implications for the design of future clinical trials of this and other vaccine candidates and highlight...

2013-03-14 17:23:00

When someone has a stroke, time equals brain. The longer a stroke is left untreated, the more brain tissue is lost. Since the only proven treatment – a clot-busting drug – works in less than half of patients, stroke physicians had high hopes for a mechanical device that could travel through the blocked blood vessel to retrieve or break up the clot, restoring blood flow to the brain. But in a recently completed multi-site trial in which UCLA served as the clinical coordinating...

2013-03-11 15:08:13

Phase 3 findings published in NEJM provide answers about treatment with darbepoetin alfa Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients —darbepoetin alfa — does not improve patients' health, nor does it reduce their risk of death from heart failure. Results of the international study were presented at the American College of Cardiology's annual meeting in San...

2013-03-07 23:56:50

Different priorities from physicians, patients weaken opportunities for genuine reform The wide consensus that health care spending poses a threat to the nation's fiscal solvency has led to the championing of "value" as a goal of health care reform efforts. But the divergence of opinions between patients and physicians on the meaning of value presents an obstacle to progress in achieving genuine reform, says Lisa Rosenbaum, MD, a Robert Wood Johnson Foundation Clinical Scholar and...

2013-03-07 23:55:16

As baby-boomers age and the number of people with serious chronic illnesses continues to rise, the demand for experts in palliative medicine is sure to outstrip the supply, according Timothy E. Quill, M.D., professor of Medicine, Psychiatry and Medical Humanities in the Center for Ethics, Humanities and Palliative Care at the University of Rochester Medical Center. In a perspective published in today's New England Journal of Medicine, Quill, who serves as president of the American Academy...

2013-02-07 12:24:59

Researchers have discovered a gene associated with a form of cholesterol that increases the risk of developing aortic stenosis, the most common form of heart valve disease, by more than half. This international study, involving the Research Institute of the McGill University Health Centre (RI-MUHC), is the first of its kind to uncover a genetic link with aortic valve disease — a condition that affects more than 5 million people in North America. The results of the study, published in...

2013-02-07 12:22:59

Study described in the New England Journal of Medicine is the first to show cause-and-effect relationship between a gene variant and calcium deposits on the aortic valve Researchers have found a genetic variant that doubles the likelihood that people will have calcium deposits on their aortic valve. Such calcification, if it becomes severe, can cause narrowing or a blockage of the aortic valve, a condition called aortic stenosis. The study is the first large-scale, genome-wide association...

2013-02-07 12:21:01

An international collaboration of researchers from the U.S. Army Medical Research and Materiel Command (USAMRMC), Tunisia and France has demonstrated a high cure rate and remarkably few side effects in treating patients with cutaneous leishmaniasis (CL) with an investigational antibiotic cream. CL is a parasitic disease that causes disfiguring lesions, with 350 million people at risk worldwide and 1.5 million new cases annually, including U.S. military personnel serving abroad and the...


Word of the Day
jument
  • A beast of burden; also, a beast in general.
'Jument' ultimately comes from the Latin 'jugum,' yoke.
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