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Latest New England Journal Stories

2012-12-06 11:16:07

As lawmakers on both sides of the political aisle look for ways to reduce federal spending in the coming weeks Medicaid may emerge as a prime target, according to a new analysis by Professor Sara Rosenbaum, JD, the Harold and Jane Hirsh Professor of Health Law and Policy at the George Washington University School of Public Health and Health Services (SPHHS). The analysis, which appears online December 5 in the New England Journal of Medicine, indicates that severe cuts to the Medicaid program...

2012-11-29 15:01:16

Boston, MA — An analysis of newly released polls shows that most of those who voted for President Obama in the 2012 election favor implementing the Affordable Care Act (ACA) and want the federal government to continue efforts to make sure most Americans have health insurance coverage. However, at the same time the President was re-elected, Republicans maintained a majority in the U.S. House of Representatives, and 30 of the nation's 50 states will have Republican governors. The...

2012-11-29 14:56:43

HOUSTON — A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine. All 12 patients in the trial with chronic phase CML and the T315I mutation had a complete hematologic response (absence of CML cells in the blood) after treatment with ponatinib. Eleven had a major reduction in CML cells in the bone marrow and nine achieved a...

2012-11-29 14:42:24

(Boston) — In a perspective article to appear in the Nov. 29 issue of the New England Journal of Medicine, researchers from Boston University Schools of Medicine and Public Health (BUSM and BUSPH) report that health-care providers can play a critical role in helping to reduce and prevent intimate partner violence (IPV) by screening and referring patients to appropriate resources. The U.S. Centers for Disease Control and Prevention recently released a comprehensive report on the...

2012-11-23 10:52:09

Immune globulin replacement began decades ago as a treatment for patients who could not make their own protective antibodies, but has proven to have much broader benefits than originally expected. With new uses regularly being discovered for this limited and expensive resource, including as a potential treatment for Alzheimer's disease, now is the time to discover exactly how intravenous immune globulin (IVIG) treatments work, and to engineer a protein that can provide similar benefits,...

2012-11-09 10:55:32

Physicians at Boston Medical Center (BMC) have developed a training video for health care providers about how to effectively use capnography to monitor ventilation and carbon dioxide levels for patients under anesthesia or conscious sedation. This is the sixth video published in the New England Journal of Medicine's Videos in Clinical Medicine section produced by BMC. It highlights the importance of using capnography to increase patient safety. Capnography, which graphically monitors...

2012-11-08 11:26:04

Electronic health records (EHRs) are expected to improve patient safety, but they themselves can present challenges for which health care providers must be prepared. Experts at The University of Texas Health Science Center at Houston and Baylor College of Medicine have proposed a framework to help develop new national patient safety goals unique to electronic health record-enabled clinical settings. Their report appears in the current issue of the New England Journal of Medicine....

2012-11-05 15:06:16

In one of the largest and longest trials involving patients with kidney failure, a study led by an international team of researchers found that cinacalcet – a drug commonly prescribed to patients with kidney failure and a disturbance of bone and mineral metabolism known as secondary hyperparathyroidism – does not significantly reduce the risk of death or major cardiovascular events. The results of the trial known as EVOLVE, which enrolled nearly 4,000 kidney patients from...

2012-11-05 15:03:03

A drug therapy shows promise for treating an inherited form of kidney disease called autosomal dominant polycystic kidney disease (ADPKD), Mayo Clinic researchers say. The medication, tolvaptan, slowed the pace of kidney cyst growth over the three years of the study. The phase three clinical trial results were being presented today at the American Society of Nephrology annual meeting and published online in the New England Journal of Medicine. The multicenter study found tolvaptan...

2012-11-01 10:15:34

Reforming Medicare payments based on large geographic regions may be too bluntly targeted to promote the best use of health care resources, a new analysis from the University of Pittsburgh Graduate School of Public Health suggests. The analysis will be published in the Nov. 1 issue of the New England Journal of Medicine. "Much policy attention has been drawn to the large geographic variation in health care spending across regions, and for good reason — because regional variation...