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Last updated on April 16, 2014 at 1:21 EDT

Latest NF-κB Stories

2014-03-14 08:27:16

CAMBRIDGE, Mass., March 14, 2014 /PRNewswire/ -- Catabasis Pharmaceuticals Inc. today announced that data from its Phase 1 clinical trial of SMART Linker conjugate CAT-1004 will be presented at the Muscular Dystrophy Association's 2014 Clinical Conference in Chicago, Ill. Catabasis' chief medical officer, Joanne Donovan, M.D., Ph.D., will discuss Duchenne muscular dystrophy (DMD) animal model data and data from a Phase 1 clinical trial during the poster session from 6:00 to 8:00 p.m. CDT on...

2014-02-20 12:15:21

St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that the alteration drives tumor development. The research appears...

2014-02-19 16:23:43

St. Jude Children's Research Hospital -Washington University Pediatric Cancer Genome Project identifies the most common genetic alteration yet in the brain tumor ependymoma; results offer clues for fighting other cancers MEMPHIS, Tenn., Feb. 19, 2014 /PRNewswire-USNewswire/ -- The St. Jude Children's Research Hospital-Washington University Pediatric Cancer Genome Project has identified the most common genetic alteration ever reported in the brain tumor ependymoma and evidence that...

2013-07-23 11:45:23

A gene long presumed dead comes to life under the full moon of inflammation, Stanford University School of Medicine scientists have found. The discovery, described in a study to be published July 23 in eLife, may help explain how anti-inflammatory steroid drugs work. It also could someday lead to entirely new classes of anti-inflammatory treatments without some of steroids' damaging side effects. Chronic inflammation plays a role in cancer and in autoimmune, cardiovascular and...

2013-04-17 15:54:07

Cell-permeable peptide hampers inflammation and atherosclerosis in mice, report investigators in The American Journal of Pathology Atherosclerosis — sometimes called "hardening of the arteries" — is a leading cause of death and morbidity in Western countries. A cell-permeable peptide containing the NF-ĸB nuclear localization sequence (NLS) shows promise as a potential agent in controlling the development of atherosclerotic disease. This study is published in the May...

2013-03-20 23:00:30

Chronic inflammation contributes to a host of medical conditions affecting people, companion pets and horses but being proactive can help keep that inflammation under control. Cur-OST® is a curcumin based all natural anti-inflammatory supplement that has demonstrated the ability to reduce chronic inflammation through modulation of two key transcription factors; NF-kB and NRF2, thereby reducing inflammation and also enhancing the immune response which may impact a variety of clinical...

2013-02-11 08:25:55

CAMBRIDGE, Mass., Feb. 11, 2013 /PRNewswire/ -- Catabasis Pharmaceuticals, Inc., today announced that a three-part series of Phase 1 studies showed that CAT-1004, a SMART Linker conjugate of docosahexaenoic acid (DHA) and salicylate created using the company's proprietary technology, was safe and well tolerated. Data also show that the conjugated compound was absorbed following oral administration and metabolized to its active components intracellularly, providing proof of concept for the...

2013-01-31 12:28:04

GLEN ALLEN, Va., Jan. 31, 2013 /PRNewswire/ -- Star Scientific, Inc. (NASDAQ: STSI) today announces publication of the first peer-reviewed article examining the effects of anatabine in a mouse model of the debilitating autoimmune and neurodegenerative disease multiple sclerosis (MS). The study, conducted by the Company's research partner, The Roskamp Institute, was designed to determine whether anatabine had beneficial effects on the development of experimental autoimmune encephalomyelitis...

2013-01-04 11:02:11

Researchers at Mayo Clinic in Florida have identified a new target to improve treatment of pancreatic ductal adenocarcinoma cancer, which accounts for more than 95 percent of pancreatic cancer cases. This fast-growing, often lethal cancer is resistant to conventional chemotherapy. The findings are published in the Jan. 3 online issue of PLOS ONE. The researchers decoded a molecular pathway that is switched "on" at all times, promoting accelerated growth of pancreatic tumors, and that...

2012-11-21 06:20:29

This discovery holds the potential to reduce healthcare costs for many common inflammatory diseases such as cancer and diabetesSingapore, Nov 21, 2012 - (ACN Newswire) - A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes. This enzyme,...