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Latest NF-κB Stories

2012-11-21 06:20:29

This discovery holds the potential to reduce healthcare costs for many common inflammatory diseases such as cancer and diabetesSingapore, Nov 21, 2012 - (ACN Newswire) - A*STAR scientists have identified the enzyme, telomerase, as a cause of chronic inflammation in human cancers. Chronic inflammation is now recognized as a key underlying cause for the development of many human cancers, autoimmune disorders, neurodegenerative diseases, and metabolic diseases such as diabetes. This enzyme,...

Loneliness Decreases In Adults Who Use Meditation
2012-08-15 12:59:06

Connie K. Ho for redOrbit.com — Your Universe Online Loneliness cannot only be damaging for the psyche, but also has physical impacts. Researchers from the University of California, Los Angeles (UCLA) found that a meditation program, completed in a little less than eight weeks, helped decrease loneliness among adults. The UCLA study also finds that mindfulness can also help boost the immune system. The findings, featured in a recent online edition of the journal Brain, Behavior...

2012-07-31 12:27:31

During Alzheimer's disease, 'plaques' of amyloid beta (Ab) and tau protein 'tangles' develop in the brain, leading to the death of brain cells and disruption of chemical signaling between neurons. This leads to loss of memory, mood changes, and difficulties with reasoning. New research published in BioMed Central's open access journal Alzheimer's Research & Therapy, has found that up-regulating the gene Hes1 largely counteracted the effects of Ab on neurons, including preventing cell...

2012-06-19 23:50:48

Researchers at the IMIM (Institut de Recerca Hospital del Mar) have proven that the absence of the 14-3-3 protein sigma in breast cancer cells is directly associated with these cells´ capacity to activate the signalling of a protein complex called NF-kB, which is related to tumor progression. The activation of NF-kB in tumors was also identified as the best indicator for relapse in breast cancer patients, compared to other parameters currently used, such as the presence of affected...

2012-05-24 22:00:51

Acute inflammatory diseases, such as sepsis, as well as chronic inflammatory diseases like diabetes and arthritis, develop as a result of sustained inflammation of the blood vessel wall. Researchers at Brigham and Women's Hospital (BWH) have discovered that a microRNA (small, non-coding RNA molecule) called miR-181b can reduce the inflammatory response that is responsible for such diseases. The findings, by researchers led by Mark Feinberg, MD from BWH and Harvard Medical School, will pave...

2012-05-16 22:24:14

Scientists optimistic that targeting pathway's cellular transcription process will lead to death of multiple myeloma cells Researchers at NYU School of Medicine have identified a target for slowing the progression of multiple myeloma by using currently available drugs. Published recently in Nature Cell Biology, the study reveals a pathway that, if deactivated, may help slow the development of the disease. "We have the ability to target this pathway with drugs that already exist,"...

2012-03-14 09:33:42

Discovered the molecular mechanism responsible for vertebral column degeneration Italian researchers at the Catholic University of Sacred Heart in Rome found an important molecular mechanism responsible for low back pain and other acute vertebral problems like cervical axial pain, all due to aging and degeneration of the vertebral column. The team led by Dr. Luigi Aurelio Nasto and Enrico Pola also developed an experimental drug to inhibit this degenerative mechanism, by blocking its...

2012-02-16 14:38:16

Scientists discover that a regulator of inflammation plays a key role in the proliferation of lung cancer cells Drugs targeting an enzyme involved in inflammation might offer a new avenue for treating certain lung cancers, according to a new study by scientists at the Salk Institute for Biological Studies. The scientists discovered that blocking the activity of the enzyme IKK2, which helps activate the body's inflammation response, slowed the growth of tumors in mice with lung cancer...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'kardia,' heart.
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