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Latest NFAT Stories

2013-06-05 13:17:04

Researchers at Lund University in Sweden have discovered how to stop the destructive process that leads to cardiovascular disease in diabetic laboratory animals. It is well known that high blood sugar levels significantly raise the risk of cardiovascular disease. It is unclear, however, why this happens. An important part of the explanation may be NFAT, a protein activated when blood sugar is raised and which starts a chain of events that damage the blood vessels and accelerate the...

2010-06-23 09:24:00

LA JOLLA, Calif., June 23 /PRNewswire/ -- CalciMedica announced the appointment of Steven L. Schoenfeld, MD, as Vice President, Clinical Development. Dr. Schoenfeld's successful, clinical drug development career spans over 20 years in the pharmaceutical and biotechnology industries. He will lead CalciMedica's development efforts, assuming immediate responsibility for advancing its first CRAC Channel Inhibitor (CCI) product candidate through IND filing and into clinical development. "Steve...

2010-02-16 08:00:00

LA JOLLA, Calif., Feb. 16 /PRNewswire/ -- CalciMedica today announced that the US Patent and Trademark Office has issued to CalciMedica US Patent No. 7,645,588, a composition patent involving STIM1, a key component of the calcium release-activated calcium (CRAC) channel. The patent, entitled "Composition comprising a cell comprising a STIM1 protein and an agent that modulates intracellular calcium and methods of use," has a priority date of March 4, 2003 and was issued on January 12, 2010....

2009-06-15 10:28:15

Scientists from A*STAR's Singapore Immunology Network (SIgN) and the University of Milano-Bicocca, Italy, have discovered another signaling pathway for the activation and apoptosis, or programmed cell death, of dendritic cells[1] . This discovery was published in the advanced online publication of Nature on 15 Jun 2009. Led by Prof Paola Castagnoli, Scientific Director of SIgN and Associate Prof Francesca Granucci of the University of Milano-Bicocca, the team discovered that the...


Word of the Day
sough
  • A murmuring sound; a rushing or whistling sound, like that of the wind; a deep sigh.
  • A gentle breeze; a waft; a breath.
  • Any rumor that engages general attention.
  • A cant or whining mode of speaking, especially in preaching or praying; the chant or recitative characteristic of the old Presbyterians in Scotland.
  • To make a rushing, whistling, or sighing sound; emit a hollow murmur; murmur or sigh like the wind.
  • To breathe in or as in sleep.
  • To utter in a whining or monotonous tone.
According to the OED, from the 16th century, this word is 'almost exclusively Scots and northern dialect until adopted in general literary use in the 19th.'
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