Latest Nicotinic acetylcholine receptor Stories

2009-04-06 16:17:59

Nicotine isn't just addictive, it may also interfere with dozens of cellular interactions in the body, U.S. researchers suggest. Brown University researchers say the data could help scientists develop better treatments for various diseases. It opens several new lines of investigation, lead author Edward Hawrot says in a statement. Hawrot and a team that included graduate students William Brucker and Joao Paulo looked specifically at the alpha-7 nicotinic acetylcholine receptor in mouse brain...

2008-11-18 09:25:18

Scientists have identified a relationship between two proteins in the brain that has links to both nicotine addiction and autism. The finding has led to speculation that existing drugs used to curb nicotine addiction might serve as the basis for potential therapies to alleviate the symptoms of autism. The discovery identified a defining role for a protein made by the neurexin-1 gene, which is located in brain cells and assists in connecting neurons as part of the brain's chemical...

2008-10-01 15:00:50

U.S. biophysicists say they have clarified the mysterious interaction between cholesterol and the brain's neurotransmitter receptors. University of Pennsylvania scientists said they have provided a new model of behavior for the nicotinic acetylcholine receptor, a well studied protein involved in inflammation, Alzheimer's disease, Parkinson's disease, schizophrenia, epilepsy, the effect of general anesthetics and addiction to alcohol, nicotine and cocaine. As a result of the study,...

2008-01-09 15:00:00

Research and Markets (http://www.researchandmarkets.com/reports/c78985) has announced the addition of Pipeline Report - Neuronal Alpha 7 Nicotinic Receptors: Candidates for the Treatment of Alzheimers Disease and Schizophrenia to their offering. Neuronal alpha 7 nicotinic receptor (a7nAChR) ligands represent an emerging class of drug for the treatment of various CNS disorders associated with cognitive dysfunction. This report describes the proof of concept supporting the development of this...

2007-01-29 16:00:00

BETHESDA, MD -- Cigarette smoke (CS) is the most preventable cause of death and chronic disease in the United States. In addition to being a risk factor for atherosclerosis and cancer, recent epidemiologic studies suggest that cigarette smoke promotes the progression of kidney disease. The mechanisms by which cigarette smoke may accelerate some types of chronic kidney disease are currently unknown. A new study, being published by the American Physiological Society (http://www.the-aps.org/),...

2006-08-15 07:20:00

NEW YORK -- Varenicline, a non-nicotine drug designed specifically for smoking cessation, appears to be safe and effective according to a study in the Archives of Internal Medicine. Varenicline is FDA-approved and marketed by Pfizer as Chantix. It binds to a nicotine receptor that's believed to trigger the rewarding effects felt with smoking. Because varenicline competes more strongly than nicotine to bind to the receptor, yet has less of a rewarding effect, the investigators figured that it...

2005-09-01 23:35:00

New Haven, Conn.- A new study by Yale researchers shows that prior nicotine exposure in mice can increase their motivation to respond work for food, weeks after their last exposure to nicotine, a finding that runs counter to the popular belief that nicotine exposure curbs appetite. The study, to be published in an upcoming issue of Psychopharmacology, also sheds new light on the role played by certain nicotinic acetylcholine receptors when it comes to the reinforcing aspects of nicotine....

Word of the Day
  • A cloth or covering, more or less ornamented, laid over the saddle or furniture of a horse, especially of a sumpter-horse or horse of state.
  • Clothing, especially sumptuous clothing; equipment; outfit.
  • To cover with a caparison, as a horse.
  • To dress sumptuously; adorn with rich dress.
This word ultimately comes from the Medieval Latin 'cappa,' cloak.