Latest Nitriles Stories

Nortriptyline has been found to cause a ten-fold increase in suicidal thoughts in men when compared to its competitor escitalopram. These findings are published in the open access journal BMC Medicine.The research was carried out by Dr. Nader Perroud from the Institute of Psychiatry, Kings College London, who headed up GENDEP, an international team. Dr Perroud said "Suicidal thoughts and behaviors during antidepressant treatment have prompted warnings by regulatory bodies". He continued "the...

DETROIT, Oct. 2 /PRNewswire-FirstCall/ -- Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD) announced that, as part of the previously announced settlement of the legal proceedings related to Lexapro® (escitalopram oxalate) tablets, it closed an Asset Purchase Agreement ("APA") transaction with Forest Laboratories, Inc. ("Forest") to acquire several products from Forest's Inwood line of business. The ANDA patent litigation settlement resolves litigation involving Caraco, Forest,...

Brain-wave patterns may predict how effective medication will beIt is a long, slow slog to treat major depression. Many antidepressant medications are available, but no single biomarker or diagnostic test exists to predict which one is right for an individual. As a result, for more than half of all patients, the first drug prescribed doesn't work, and it can take months to figure out what does.Now, based on the final results of a nationwide study led by UCLA, clinicians may be able to...

WALTHAM, Mass., Aug. 17 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that although generic erosion will negatively impact the major depression drug market in the United States, patent protection of key blockbuster agents will help drive market growth in Europe and Japan through 2018. The new Pharmacor report entitled Major Depressive Disorder finds that sales of therapies for major depression in...

Police in Wisconsin said a woman and her husband's three mistresses have been arrested for an alleged revenge plot involving a motel room and powerful glue. Investigators said one of the mistresses, Therese Ziemann, 48, lured the 36-year-old man to a Stockbridge motel with promises of a rub down and he was blindfolded and tied to the bed before the other three women entered the room, the Chicago Tribune reported Tuesday. The women threatened the man with mace, punched him in the face and...

NEW YORK, July 10, 2009 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX) and its wholly-owned subsidiary, Forest Laboratories Holdings, Ltd. (collectively, "Forest"), and H. Lundbeck A/S ("Lundbeck") announced today that they have entered into a settlement agreement with Sun Pharmaceutical Industries Ltd. ("Sun Pharma", a reference that includes its 100% subsidiaries) and Caraco Pharmaceutical Laboratories, Ltd. ("Caraco"), regarding pending patent infringement disputes...

DETROIT, July 10 /PRNewswire-FirstCall/ -- Caraco Pharmaceutical Laboratories, Ltd. (NYSE Amex: CPD) announced that, as part of the settlement of the legal proceedings related to Lexapro(R) (escitalopram oxalate) tablets, it entered into an Asset Purchase Agreement with Forest Laboratories, Inc. ("Forest") to acquire several products from Forest's Inwood line of business. The ANDA patent litigation settlement resolves litigation involving Caraco, Forest, Forest Holdings, Ltd., and H....

Depression in older adults too often goes unrecognized and untreated, resulting in untold misery, worsening of medical illness, and early death. A new study has identified one important remedy: Adding a trained depression care manager to primary care practices can increase the number of patients receiving treatment, lead to a higher remission rate of depression, and reduce suicidal thoughts. The two-year outcomes of the multicenter Prevention of Suicide in Primary Care Elderly:...

Following results of a new study, researchers question the efficacy of the antidepressant, citalopram, for the treatment of repetitive behaviors in children with autism.Citalopram is in a class of antidepressants know as selective serotonin reuptake inhibitors (SSRIs), designed to interfere with the way the brain regulates serotonin."Despite the relative dearth of evidence supporting their use, SSRIs are among the most frequently used medications for children with autism, partially...

U.S. researchers found the antidepressant drug citalopram was no better than a placebo in treating autism behavior such as spinning or rocking. The multicenter, 12-week clinical trial involving 149 children ages 5-17 was directed by the Feinstein Institute for Medical Research in Manhasset, N.Y. The researchers suggest the study, published in the Archives of General Psychiatry, should serve to reduce the number of antidepressant prescriptions written for children with autism and similar...