Latest nitroglycerin Stories

Researchers at Queen’s University have identified a new mechanism that could potentially explain why the body’s immune system sometimes fails to eliminate cancer. The new findings shed light on the possible cause of immune resistance in cancer cells, and indicate that nitroglycerin, a relatively safe and low-cost drug used for more than a century to treat angina, may be effective for managing certain cancers. “This discovery may lead to new approaches for the treatment of patients...

When given for hours as a continuous dose, the heart medication nitroglycerin backfires -- increasing the severity of subsequent heart attacks, according to a study of the compound in rats by researchers at the Stanford University School of Medicine. "Basically it's a cautionary tale," said professor of chemical and systems biology Daria Mochly-Rosen, PhD, senior author of the study that will be published Nov. 2 in Science Translational Medicine. "Here is a practice in medicine used for...

Indicated for acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease Cranford, NJ (PRWEB) March 16, 2011 Coronary artery disease (CAD), also known as coronary heart disease, is the most common type of heart disease, currently affecting about 17 million Americans.(1) Most of these people suffer from a common symptom of CAD known as angina pectoris. For over 100 years, physicians have treated acute angina with nitrates, the most common form being...

CRANFORD, N.J., March 16, 2011 /PRNewswire/ -- Coronary artery disease (CAD), also known as coronary heart disease, is the most common type of heart disease, currently affecting about 17 million Americans(1). Most of these people suffer from a common symptom of CAD known as angina pectoris. For over 100 years, physicians have treated acute angina with nitrates, the most common form being nitroglycerin(2). Considered the gold standard in treating acute angina, nitroglycerin tablets have had...

By: Rhonda Craig, Ivanhoe Health Correspondent(Ivanhoe Newswire) -- The same medicines used to treat angina and chronic heart failure, may also help treat osteoporosis. In this new study, researchers found that postmenopausal women that used nitroglycerin ointment for two years experienced a modest increase in bone mineral density and decrease in bone loss.According to study authors, the number of osteoporotic fractures is increasing, and an inexpensive and widely available treatment like...

Preliminary research indicates that use of nitroglycerin ointment among postmenopausal women for 2 years was associated with a modest increase in bone mineral density and decrease in bone resorption (loss), according to a study in the February 23 issue of JAMA."The number of osteoporotic fractures is increasing worldwide as populations age. An inexpensive and widely available treatment may help limit this increase," the authors write. "Nitroglycerin stimulates bone formation...

SILVER SPRING, Md., March 16 /PRNewswire-USNewswire/ -- The U.S. Food and Drug Administration today ordered Glenmark Generics of Mahwah, N.J., and Konec Inc. of Tucson, Ariz., to stop marketing unapproved nitroglycerin tablets. The tablets are placed under the tongue to relieve chest pain or to stop a heart attack and are marketed in 0.3 mg, 0.4 mg, and 0.6 mg dosages. (Logo: http://www.newscom.com/cgi-bin/prnh/20090824/FDALOGO) The FDA does not anticipate a supply problem for these...

Treatment of prostate cancer using a very low dose of nitroglycerin may slow and even halt the progression of the disease without the severe side effects of current treatments, Queen's University researchers have discoveredThe findings are the result of the first-ever clinical trial using nitroglycerin to treat prostate cancer.The 24-month, Phase II study targeted 29 men with increasing levels of prostate-specific antigen (PSA) following prostate surgery or radiation. PSA levels are a key...

The U.S. Food and Drug Administration announced the nationwide recall of a dietary supplement sold under the name Steam. The FDA said Nutracoastal Trading LLC of Freeport, N.Y., is voluntarily recalling Steam lot 90260 because it contains Tadalafil, an active ingredient of an FDA-approved drug used for erectile dysfunction. The inclusion of the drug makes Steam dietary supplement an unapproved drug, the FDA said. The undeclared ingredient may interact with nitrates found in some prescription...

The reaction causing bioactivation is not well understoodSo-called nitrovasodilators such as nitroglycerin have been used effectively in the treatment of angina pectoris in coronary heart disease for more than century. Within the human body, nitric oxide (NO) is released from the nitroglycerin and in turn stimulates an enzyme that dilates the arteries and thus improves blood circulation. In 1998, Robert F. Furchgott, Ferid Murad and Louis Ignarro were awarded the Nobel Prize for Medicine for...