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Latest NMDA receptor Stories

2014-06-11 23:11:43

The article published in AIMS Neuroscience explains how cortical microcircuitry is conducive to column formation. The column is the information bit proposed in the Dimensional Systems Model as the basis for learning and memory. Greenville, SC (PRWEB) June 11, 2014 Clinical neuropsychologist Robert A. Moss, Ph.D., FACPN, FAACP, and cognitive psychologist Jarrod Moss, Ph.D., are the authors of an article on cortical columns in the explanation of gamma-band synchrony and NMDA receptors in...

2014-05-26 13:27:58

Canadian Association for Neuroscience Mechanism uncovered could also help preserve neuron function in Alzheimer's disease, traumatic brain injury and other neurodegenerative conditions Research presented by Dr. Lynn Raymond, from the University of British Columbia, shows that blocking a specific class of glutamate receptors, called extrasynaptic NMDA receptors, can improve motor learning and coordination, and prevent cell death in animal models of Huntington disease. As Huntington...

2014-05-15 08:31:53

EVANSTON, Ill., May 15, 2014 /PRNewswire/ -- Naurex Inc. today announced that its president and chief executive officer, Norbert G. Riedel, PhD, will present at the UBS Global Healthcare Conference on Monday, May 19, 2014 at 1:00 p.m. EDT. Dr. Riedel will provide an overview of the company and discuss its two clinical-stage rapid-acting antidepressant drug candidates, GLYX-13 and NRX-1074. Last week Naurex reported positive top-line Phase 2b results for GLYX-13 and the advancement...

2014-05-06 08:34:13

- Lead NMDA Receptor Modulator GLYX-13 Shows Robust and Sustained Antidepressant Effects with Repeat Dosing and Is Well-Tolerated in Subjects with Difficult-to-Treat Depression - EVANSTON, Ill., May 6, 2014 /PRNewswire/ -- Naurex Inc., a privately held biopharmaceutical company leveraging its unique platform to develop novel drugs for diseases of the central nervous system (CNS), today announced that its two lead antidepressant programs achieved major milestones. Top-line results...

2014-03-03 08:31:02

EVANSTON, Ill., March 3, 2014 /PRNewswire/ -- Naurex Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation to the investigation of GLYX-13, the company's rapid-acting antidepressant in Phase 2 clinical development, as adjunctive therapy in major depressive disorder. GLYX-13 has shown rapid-acting antidepressant activity with excellent safety in a single-dose Phase 2a clinical study in subjects who had failed treatment with existing...

2014-01-08 08:28:22

- Former Baxter International Executive Takes Helm as Neuropharmaceutical Innovator Prepares for Late-Stage Trials of its Novel Mechanism NMDA Receptor Modulators - EVANSTON, Ill., Jan. 8, 2014 /PRNewswire/ -- Naurex Inc. today announced that Norbert G. Riedel, Ph.D., has been named president and chief executive officer effective January 1, 2014. Naurex's founding chief executive officer Derek Small will continue as a director of the company. Naurex is a biopharmaceutical company...

2014-01-07 23:02:06

Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. Pomona, California (PRWEB) January 07, 2014 Two new publications by a team from Western University of Health Sciences shed further light on the mechanisms of learning and memory, and neuronal degeneration. The first paper, “A molecular brake controls the magnitude of long-term potentiation,” by Yubin Wang, Guoqi Zhu, Victor...

2013-12-05 23:40:35

The N-methyl-D-aspartic acid (NMDA) receptor dysfunction in the brain of aged animals has been shown. In older rodents, N-methyl-D-aspartate receptor 2B subunit gene expression declines significantly associated with memory impairment. To further reveal this process, Dr. Chunxia Li and colleagues from East China Normal University, China analyzed gene expression profiles in the neocortex of aged Tg mice. Pathway and signal-net analyses identified multiple pathways altered in the transgenic...

2013-11-06 13:47:01

The pain caused by a surgical incision may contribute to the risk of postoperative cognitive dysfunction, a sometimes transient impairment in learning and memory that affects a small but significant number of patients in the days following a surgical procedure. An animal study from Massachusetts General Hospital (MGH) researchers, appearing in the November 6 Journal of Neuroscience, also identifies a probable mechanism for pain-induced cognitive impairment, suggesting pathways that may be...


Word of the Day
attercop
  • A spider.
  • Figuratively, a peevish, testy, ill-natured person.
'Attercop' comes from the Old English 'atorcoppe,' where 'atter' means 'poison, venom' and‎ 'cop' means 'spider.' 'Coppa' is a derivative of 'cop,' top, summit, round head, or 'copp,' cup, vessel, which refers to 'the supposed venomous properties of spiders,' says the OED. 'Copp' is still found in the word 'cobweb.'
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