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Latest NOD mice Stories

2012-07-06 10:14:31

Scientists at the University of North Carolina School of Medicine have used injections of antibodies to rapidly reverse the onset of Type I diabetes in mice genetically bred to develop the disease. Moreover, just two injections maintained disease remission indefinitely without harming the immune system. The findings, published online ahead of print (June 29, 2012) in the journal Diabetes, suggest for the first time that using a short course of immunotherapy may someday be of value for...

2010-08-03 07:00:00

DURHAM, N.C., Aug. 3 /PRNewswire/ -- Argos Therapeutics today announced that its Arcelis(TM) immunotherapy targeted at diabetes demonstrated potential for preventing and treating the disease in non-obese diabetic (NOD) mice, according to a peer-reviewed article published in Molecular Therapy (Creusot, R.J., et al.; doi:10.1038/mt.2010.146). The study was based on a mouse model of type 1 diabetes that shares many similarities with human models to demonstrate the therapeutic effectiveness of...

2008-10-30 18:00:11

Investigators combing the genome in the hope of finding genetic variants responsible for triggering early-onset diabetes may be looking in the wrong place, new research at the Stanford University School of Medicine suggests. Early-onset diabetes, also known as type-1 diabetes, is an autoimmune disease, caused when the immune system attacks and destroys insulin-producing cells in a person's pancreas. What triggers that immune response apparently has less to do with having a distinct...

2008-09-22 09:00:12

"Friendly" bacteria protect against Type 1 diabetes WASHINGTON, Sept. 21 (Xinhua) -- In a dramatic illustration of the potential for microbes to prevent disease, researchers at Yale University and University of Chicago showed that mice exposed to common stomach bacteria were protected against the development of Type 1 diabetes. The findings, reported in the latest issue of journal Nature, support the so-called "hygiene hypothesis" -- the theory that a lack of exposure to parasites,...