Latest Non-alcoholic fatty liver disease Stories

Three pseudo kinases of the Tribbles family have been recently recognized, which include TRB1, TRB2 and TRB3. Recent research has found that the expression of hepatic TRB3 increased in a rat model of diabetes. TRB3 could block the insulin signaling pathway through inhibiting Akt activation, which contributes to insulin resistance. A research article to be published on May 21, 2009 in the World Journal of Gastroenterology addresses this question. This research, lead by Dr. Yu-Gang Wang...

The latest research in liver disease being presented at Digestive Disease Week® 2009 (DDW®) has important implications for tracking disease development in patients and for current and future transplant recipients. Researchers are making great strides in diagnosing and treating liver disease."The research being presented during DDW shows how widespread our efforts are in understanding and treating liver disease," said Brent Tetri, MD, Saint Louis University. "These studies...

Intestinal permeability and an overgrowth of bacteria in the small intestine are both associated with nonalcoholic fatty liver disease (NAFLD). These findings are revealed in a new study in the June issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (www.interscience.wiley.com).Previous studies have suggested that bacteria from the intestine...

Women with a history of hypothyroidism face a significantly higher risk of developing liver cancer, according to a new study in the May issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience.Hypothyroidism is the most common thyroid disorder among U.S. adults, affecting between 8 and 12 percent of the U.S. population, and more women than men. The...

Poor aerobic fitness is strongly associated with obesity and its consequent risks of heart disease, strokes and diabetes "“ now considered worldwide epidemics. But the underlying link has long puzzled scientists. New research in The Journal of Physiology connects low aerobic capacity to another serious condition "“ non-alcoholic fatty liver disease (NAFLD) "“ and suggests that the resulting liver problems play a crucial step developing obesity-related illnesses.Sufferers of NAFLD...

Metabolic syndrome has a new partner in crime. Non-alcoholic fatty liver disease (NAFLD) is the latest condition stemming from poor physical fitness and may threaten your health in the same dangerous ways.Being physically unfit can put you at risk of developing NAFLD "“ a disease that causes the accumulation of fat in the liver, leading to high levels of fat in the blood stream, amplifying the risk-factors of obesity. Like alcohol abuse, NAFLD causes liver damage called fibrosis, which can...

Liver cancer in patients whose only risk factor is metabolic syndrome has distinct forms and structures compared to other liver tumors. These findings are in the March issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver Diseases (AASLD). The article is also available online at Wiley Interscience (www.interscience.wiley.com).Cancer of the liver, also known as hepatocellular carcinoma, is the fifth most common type of...

A new study suggests that the metabolic response to obesity and insulin resistance, particularly as it pertains to the liver, differs among ethnic groups in the U.S. African-Americans are more resistant to the buildup of fat in the abdominal adipose tissue and liver, and to high triglyceride levels associated with insulin resistance. These findings are in the March issue of Hepatology, a journal published by John Wiley & Sons on behalf of the American Association for the Study of Liver...

Study Evaluating Cysteamine in Collaboration with UC San Diego NOVATO, Calif., Feb. 5 /PRNewswire-FirstCall/ -- Raptor Pharmaceuticals Corp. ("Raptor" or the "Company") (OTC Bulletin Board: RPTP), today announced the completion of patient enrollment in its Phase 2a open-label clinical trial to evaluate cysteamine bitartrate ("cysteamine") in patients diagnosed with non-alcoholic steatohepatitis ("NASH"). NASH, a progressive form of liver disease that accounts for approximately 10% of...

Moms to be may have more reason to stick to a healthy diet while they're pregnant. New research indicates a developing baby's health can be affected by the amount of fat consumed by his or her mother.There has been a recent rise in the United States in the number of children classified as obese and diagnosed with obesity-related diseases, such as type 2 diabetes and nonalcoholic fatty liver disease (NAFLD). Previous studies pointed to the weight of an obese child's mother during...