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Latest Non-coding RNA Stories

2014-07-15 13:33:52

Emory Health Sciences Bacterial defense system vs phages has unexpected functions CRISPR, a system of genes that bacteria use to fend off viruses, is involved in promoting antibiotic resistance in Francisella novicida, a close relative of the bacterium that causes tularemia. The finding contrasts with previous observations in other bacteria that the CRISPR system hinders the spread of antibiotic resistance genes. The results are scheduled for publication in PNAS Early Edition....

2014-07-07 12:28:43

CRISPR/Cas9 system allows researchers to quickly and precisely edit DNA ST. LOUIS, July 7, 2014 /PRNewswire/ -- SAGE Labs Inc., a leading provider of in vivo products, services and technologies in the field of genome engineering, today launched its SAGEspeed CRISPR/Cas9 Reagents. These reagents enable researchers to quickly and easily perform genetic engineering in animal models, such as mice and rats, as well as cell lines. Since 2009, SAGE Labs has been using targeted nucleases,...

2014-06-09 14:11:57

University of California - San Francisco A double-edged sword, gene variants may promote overall health while increasing risk of gliomas New genomic research led by UC San Francisco (UCSF) scientists reveals that two common gene variants that lead to longer telomeres, the caps on chromosome ends thought by many scientists to confer health by protecting cells from aging, also significantly increase the risk of developing the deadly brain cancers known as gliomas. The genetic...

2014-06-06 09:56:06

PLOS YbeY is a conserved protein that is present in most bacteria. A study published on June 5th in PLOS Pathogens examines the function of YbeY in the cholera bacterium and reveals critical roles in RNA metabolism in this and other pathogenic bacteria. Graham Walker, from the Massachusetts Institute of Technology, USA, and colleagues previously studied E. coli YbeY and found that it acts as an "RNase"—a protein that deliberately and specifically cuts RNA molecules and thereby...

2014-05-27 23:06:48

Findings to Enhance System That Is Transforming Genetic Research Charlottesville, VA (PRWEB) May 27, 2014 Researchers at the University of Virginia School of Medicine have devised a way to detect unintended side effects of manipulating genes using a revolutionary new system that is sweeping the scientific world by storm. The gene targeting system, called CRISPR, allows editing of genetic information at specifically targeted sites in the genome. UVA’s new approach reveals the system has...

2014-05-27 11:46:17

University of Bristol An international team of scientists has made a major step forward in our understanding of how enzymes 'edit' genes, paving the way for correcting genetic diseases in patients. Researchers at the Universities of Bristol, Münster and the Lithuanian Institute of Biotechnology have observed the process by which a class of enzymes called CRISPR – pronounced 'crisper' – bind and alter the structure of DNA. The results, published in the Proceedings of the National...

2014-05-14 23:02:07

The new NextGEN™ CRISPR genome engineering tools and services provided by Transposagen are ideal when research and drug discovery applications require clean, high-precision genome editing. Lexington, KY (PRWEB) May 14, 2014 Altering the genome with targeted nucleases is powerful and increasingly necessary for research and drug discovery. The CRISPR-Cas9 system has gained popularity due to its simplicity and high efficiency. While the original CRISPR technology is not owned or...

2014-05-11 00:21:06

The NextGEN(TM) CRISPR genome engineering tools and services provided by Transposagen are ideal when research and drug discovery applications require clean, high-precision genome editing. LEXINGTON, Ky., May 11, 2014 /PRNewswire-iReach/ -- Altering the genome with targeted nucleases is powerful and increasingly necessary for research and drug discovery. The CRISPR-Cas9 system has gained popularity due to its simplicity and high efficiency. While the original CRISPR technology is not...

2014-04-28 10:17:33

A next-generation genome editing system developed by Massachusetts General Hospital (MGH) investigators substantially decreases the risk of producing unwanted, off-target gene mutations. In a paper receiving online publication in Nature Biotechnology, the researchers report a new CRISPR-based RNA-guided nuclease technology that uses two guide RNAs, significantly reducing the chance of cutting through DNA strands at mismatched sites. "This system combines the ease of use of the widely...

2014-04-28 10:11:32

Large sections of the genome that were once referred to as “junk” DNA have been linked to human heart failure, according to research from Washington University School of Medicine in St. Louis. So-called junk DNA was long thought to have no important role in heredity or disease because it doesn’t code for proteins. But emerging research in recent years has revealed that many of these sections of the genome produce RNA molecules that, despite not being proteins, still have important...


Word of the Day
penuche
  • A fudgelike confection of brown sugar, cream or milk, and chopped nuts.
'Penuche' is a variant of 'panocha,' a coarse grade of sugar made in Mexico. 'Panocha' probably comes from the Spanish 'panoja, panocha,' ear of grain.
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