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Latest Non-steroidal anti-inflammatory drug Stories

2010-06-09 05:55:00

TARRYTOWN, N.Y., June 9 /PRNewswire-FirstCall/ -- Regeneron Pharmaceuticals, Inc. (Nasdaq: REGN) today announced that a Phase 3 study in gout patients initiating allopurinol therapy to lower their uric acid levels showed that ARCALYST (rilonacept), also known as IL-1 Trap, prevented gout attacks, as measured by the primary endpoint of the number of gout flares per patient over the 16 week treatment period. Primary Endpoint: Patients who received ARCALYST at a weekly,...

2010-01-05 14:32:00

People with the heritable disorder of the skin called Gorlin syndrome who are genetically predisposed to develop basal cell carcinoma of the skin may have a new chemoprevention therapy on the horizon. According to results of a placebo-controlled, randomized, double-blind, Phase II study, the use of celecoxib was effective in inhibiting the development of basal cell carcinomas in a relatively rare group of patients who are highly susceptible to carcinoma. These findings are published in the...

2009-12-08 14:37:28

Press release from PLoS Medicine Cost-effectiveness studies are widely used to guide prescribing policy in many countries, as part of health technology assessment programs. However, a new study published this week in PLoS Medicine by Tjeerd-Pieter van Staa and colleagues suggests that cost-effectiveness analyses based on data from randomized controlled trials may not be realistic enough to accurately inform policy. In the study the researchers (affiliated with the General Practice Research...

2009-11-23 16:34:15

Provides lessons for post-market pharmaceutical safety Evidence of cardiovascular risks associated with taking Vioxx, the popular, nonsteroidal anti-inflammatory drug (rofecoxib), could have been identified nearly four years before its manufacturer, Merck & Co. Inc., voluntarily pulled the drug from the market. Led by Joseph Ross, MD, MHS, Assistant Professor of Geriatrics and Palliative Medicine and of Medicine at Mount Sinai School of Medicine, a team of six investigators analyzed 30...

2009-11-18 14:55:22

Indomethacin has been proved by epidemiological and experimental studies to be closely associated with peptic ulcer development. Vardenafil is a potent phosphodiesterase 5 inhibitor and its effects on the gastric mucosa havenot been reported. A research article to be published in October 28, 2009 in the World Journal of Gastroenterology addresses this question. The research team, led by Dr. Karakaya MD from Zonguldak Karaelmas University, designed an experimental study in rat which they used...

2009-05-29 16:57:19

People who drank tart cherry juice while training for a long distance run reported less pain after exercise than those who didn't, U.S. researchers said. Researchers at Oregon Health & Science University studied 60 healthy adults ages 18-50, who drank 10.5 ounces cherry juice -- 100 percent cherry juice -- twice a day for seven days prior to and on the day of a long-distance relay. They reported significantly less muscle pain following the race than those who drank another fruit juice...

2009-05-22 09:43:30

Non-steroidal anti-inflammatory drugs (NSAIDs), which are known to reduce the risk of colon cancer, act directly on cyclooxygenase-2 (COX2) and reduce its activity. Population studies have found an association of inherited variations in the COX2 gene with colon cancer risk, but others were unable to replicate this finding. Similarly, variations in the uridine diphosphate glucuronosyltransferase 1A6 (UGT1A6) gene, which is also known to be key in the metabolism of NSAIDs, have been shown to...

2009-05-04 07:00:00

- Company Also Submits sNDA for NEXIUM Capsules for Risk Reduction of Low-Dose Aspirin-Associated Peptic Ulcer - WILMINGTON, Del., May 4 /PRNewswire-FirstCall/ -- AstraZeneca (NYSE: AZN) today announced the submission of a new drug application (NDA) to the U.S. Food and Drug Administration (FDA) seeking approval for a product combining low dose aspirin with esomeprazole magnesium for the risk reduction of low dose aspirin-associated gastric and/or duodenal ulcers in patients at risk....

2009-04-17 12:51:11

One lab's groundbreaking approach to tailoring drugs that meet only a specific target within the body has focused on anti-inflammatory, anti-AIDS and anti-cancer drugs since 1982 Corticosteroids are powerful drugs used to treat inflammatory conditions such as asthma and other chronic diseases which has made them among the most widely prescribed drugs. Although the anti-inflammatory drugs offer swift relief to the patient, they can carry with them serious side effects. For example, the...

2009-04-09 03:43:00

JAKARTA, Indonesia, April 9 /PRNewswire/ -- Rheumatoid arthritis (RA) is a systemic disease or an autoimmune disorder in which the body's defense system attacks the joints through the thin layer of cells called the synovium that lines and lubricates the joints. The most visible symptoms of RA are swollen joints and crippling stiffness, particularly of the hands and feet. It can cause fatigue, fever, loss of appetite and also impedes mobility and quality of life. (Logo:...


Word of the Day
ween
  • To think; to imagine; to fancy.
  • To be of opinion; have the notion; think; imagine; suppose.
The word 'ween' comes from Middle English wene, from Old English wēn, wēna ("hope, weening, expectation"), from Proto-Germanic *wēniz, *wēnōn (“hope, expectation”), from Proto-Indo-European *wen- (“to strive, love, want, reach, win”).
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