Latest Norepinephrine Stories
Scientists may have discovered why the standard treatment for Parkinson's disease is often effective for only a limited period of time. Their research could lead to a better understanding of many brain disorders, from drug addiction to depression, that share certain signaling molecules involved in modulating brain activity. A team led by Bernardo Sabatini, Takeda Professor of Neurobiology at Harvard Medical School, used mouse models to study dopamine neurons in the striatum, a region of...
Beta blockers prevent the negative effects of stress Stressed people fall into habits and their behavior is not goal-directed. That the neurotransmitter norepinephrine plays a decisive role here is now reported in the Journal of Neuroscience by scientists from Bochum led by Dr. Lars Schwabe (RUB Faculty of Psychology). If the effect of norepinephrine is stopped by beta blockers, the stress effect does not occur. "The results may be important for addictive behaviors, where stress is a key...
Researchers at the University of Illinois at Chicago have shown for the first time that damage to a particular area of the brain and a consequent reduction in noradrenaline are associated with multiple sclerosis.The study is available online in the journal Brain.The pathological processes in MS are not well understood, but an important contributor to its progression is the infiltration of white blood cells involved in immune defense through the blood-brain barrier.Douglas Feinstein, research...
ATLANTA - Physicians treating patients with shock should consider norepinephrine instead of dopamine as a tool for stabilizing blood pressure, according to an editorial in the March 4, 2010, issue of the New England Journal of Medicine (NEJM). Jerrold Levy, MD, FAHA, professor and deputy chair for research, Department of Anesthesiology, Emory University School of Medicine, and co-director of cardiothoracic anesthesiology, Emory Healthcare, authored the editorial.The editorial accompanies a...
Monoamine oxidase-A inhibitor drug blocks buildup of toxic free radicals in animal heartsA team of Johns Hopkins and other researchers have found in animal experiments that an antidepressant developed over 40 years ago can blunt and even reverse the muscle enlargement and weakened pumping function associated with heart failure.In a report to be published in the Jan. 8 edition of the journal Circulation Research, the international team of U.S. and Italian heart experts describes in a dozen key...
Loss of the gene that causes Rett syndrome disrupts the production of neurotransmitters in specific nerve cells, causing the movement and behavioral problems typical of the disease, said a research team led by those at Baylor College of Medicine in a report online today in the Proceedings of the National Academy of Sciences."Abnormalities in MeCP2 (methyl-CpG binding protein) lead to decreased production of enzymes that control production of the neurotransmitters dopamine, norepinephrine...
At birth, children with Down syndrome aren't developmentally delayed. But as they age, these kids fall behind. Memory deficits inherent in Down syndrome hinder learning, making it hard for the brain to collect experiences needed for normal cognitive development.Now, findings from the Stanford University School of Medicine and Lucile Packard Children's Hospital shed light on the neural basis of memory defects in Down syndrome and suggest a new strategy for treating the defects with medication....
A new study by researchers at Wake Forest University School of Medicine may reveal how long-lasting memories form in the brain.The researchers hope that the findings, now available online and scheduled to appear in an upcoming issue of Neuroscience, may one day help scientists develop treatments to prevent and treat conditions such as post-traumatic stress disorder."Although many things are known about memories that form from repeat experiences, not much is known with regard to how some...
Until now diseases like schizophrenia and bipolar disorder have been difficult to study biologically, since this would entail taking samples from the patient's brain. But new research findings from Örebro University in Sweden show that it is just as good to study a certain type of skin cells, since they function in a way that is similar to a type of brain cells that are suspected of playing a major role in both disorders."Among other benefits, this makes it considerably easier to develop...
Genetic differences explain why some are predisposed to shock and kidney troubles; gene test guides treatment post operationGenetic differences can explain why some patients undergoing heart surgery later experience shock and kidney complications, according to a study appearing in an upcoming issue of the Journal of the American Society Nephrology (JASN). The results indicate that performing a genetic test on patients before they have surgery can help guide treatment after they leave the...
