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Latest Nucleosome Stories

2014-06-23 08:27:29

First revenues from VolitionRx Nucleosomics technology NAMUR, Belgium, June 23, 2014 /PRNewswire/ -- VolitionRx Limited (OTCQB: VNRX), a life sciences company, today announces its first wholesale order of NuQ® Research Use Only kits to Active Motif. Each kit allows epigenetics researchers to identify and analyze a different nucleosome structure. Active Motif will distribute the kits in its key markets of Europe, the United States and Japan. These assays allow researchers -- in areas as...

Physical Reason For Shape Of Metaphase Chromosome Discovered
2014-01-15 07:37:00

Universitat Autonoma de Barcelona This work gives a solution to a fundamental question in structural biology: Why do metaphase chromosomes have their characteristic elongated cylindrical shape? The proposed solution is consistent with the structure of metaphase chromatin and with the nanomechanical properties of chromatin and chromosomes. It is a research at the interface between biology (higher order chromatin structure) and physical sciences (supramolecular structures and nanomaterials)....

2013-10-01 10:12:53

By detailing a process required for repairing DNA breakage, scientists at the Duke Cancer Institute have gained a better understanding of how cells deal with the barrage of damage that can contribute to cancer and other diseases. The insights, reported online the week of Sept. 30, 2013, in the journal Proceedings of the National Academy of Sciences, build on earlier work by the research team and identify new prospects for developing cancer therapies. The researchers have focused on a...

To Test 'Histone Code' Researchers Exploit Gene Position
2013-01-03 13:25:12

University of California - San Diego In a novel use of gene knockout technology, researchers at the University of California, San Diego School of Medicine tested the same gene inserted into 90 different locations in a yeast chromosome — and discovered that while the inserted gene never altered its surrounding chromatin landscape, differences in that immediate landscape measurably affected gene activity. The findings, published online in the Jan. 3 issue of Cell Reports,...

2012-11-19 11:36:07

A new discovery from researchers at Huntsman Cancer Institute (HCI) at the University of Utah concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases. The discovery, by Bradley R. Cairns, PhD, Senior Director of Basic Science at HCI and a professor in the Department of Oncological Sciences, is reported in this week's online...

2012-10-04 13:41:21

Scientists in Canada and the United States have used three-dimensional imaging techniques to settle a long-standing debate about how DNA and structural proteins are packaged into chromatin fibers. The researchers, whose findings are published in EMBO reports, reveal that the mouse genome consists of 10-nm chromatin fibers but did not find evidence for the wider 30-nm fibers that were previously thought to be important components of the DNA architecture. “DNA is an exceptionally long...

2012-09-17 16:58:52

The first detailed and complete picture of a protein complex that is tied to human birth defects as well as the progression of many forms of cancer has been obtained by an international team of researchers led by scientists with the U.S. Department of Energy (DOE)´s Lawrence Berkeley National Laboratory (Berkeley Lab). Knowing the architecture of this protein,  PRC2, for Polycomb Repressive Complex 2, should be a boon to its future use in the development of new and improved...


Word of the Day
cruet
  • A vial or small glass bottle, especially one for holding vinegar, oil, etc.; a caster for liquids.
This word is Middle English in origin, and ultimately comes from the Old French, diminutive of 'crue,' flask.
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