Latest Nucleosome Stories
Researchers discovered a special type of molecular structure that helps keep genes properly turned off until the structure is ejected from those genes in a regulated manner to help turn the genes on. The discovery is reported in the Oct. 21 issue of the journal Cell by scientists from the Huntsman Cancer Institute at the University of Utah. In all organisms, the genome is split into chromosomes (compressed long strands of DNA) which are subdivided into functional DNA segments called genes....
PHILADELPHIA - In their efforts to understand the complex biology of life, scientists often seek to isolate individual elements of the puzzle for study, to break the problem down to a more manageable size. Single genes and molecules are closely analyzed to better understand their specific interactions with other single entities within larger systems. Sometimes, however, this approach misses important aspects of biology that depend on higher levels of organization. Sometimes putting a few of...
New York University chemists have employed a computer simulation whose results have enhanced scientific understanding of the DNA transcription process. The study, funded by the National Institutes of Health, appears in the June 7 issue of the Proceedings of the National Academy of Sciences. Previous research has indicated that chromatin--a chromosome's substance consisting of histone proteins and DNA--exhibits salt-dependent conformations. Specifically, chains of nucleosomes, the building...
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