Latest NUP214 Stories

2011-06-20 19:50:39

Researchers at Delft University of Technology and the University of Basel have established a biomimetic nanopore that provides a unique test and measurement platform for the way that proteins move into a cell's nucleus. In the journal Nature Nanotechnology (June 19 - online), they report an artificial nanopore that is functionalized with key proteins which mimicks the natural nuclear pore. Upon testing the transport of individual proteins through the biomimetic pore, they found that most...

2010-02-04 14:46:48

Nuclear pore complexes are best known as the communication channels that regulate the passage of all molecules to and from a cell's nucleus. Researchers at the Salk Institute for Biological Studies, however, have shown that some of the pores' constituent proteins, called nucleoporins, pull double duty as transcription factors regulating the activity of genes active during early development. This is the first time nucleoporins' gene regulatory function has been demonstrated in multicellular...

2009-01-23 11:31:15

As parts of us age, even the membrane bound nuclei, which house the genetic instructions for life that are "written" in our DNA, begin to show considerable wear and tear, suggests a new report in the January 23rd issue of the journal Cell, a Cell Press publication. The nuclear pore complexes that normally act as gatekeepers--selectively importing and exporting the molecular ingredients for life to and from the nucleus--begin to break down and spring leaks. That's because some of the 30 or so...

Word of the Day
  • Like a worm in form or movement; vermiform; tortuous or sinuous; also, writhing or wriggling.
  • Like the track or trace of a worm; appearing as if worm-eaten; vermiculate.
  • Marked with fine, close-set, wavy or tortuous lines of color; vermiculated.
  • A form of rusticated masonry which is so wrought as to appear thickly indented with worm-tracks.
This word ultimately comes from the Latin 'vermis,' worm.