Latest Nutlin Stories

2013-12-24 23:02:48

A potential new cancer therapy works by “turning on” a powerful natural tumor suppressor. Raleigh, NC (PRWEB) December 24, 2013 A new study published in Cell Cycle and reported by Surviving Mesothelioma says a molecule known by the acronym RITA (reactivation of p53 and induction of tumor cell apoptosis) may work synergistically with current cancer treatments to fight mesothelioma. RITA is one of two molecules tested in the new study, which focused on the natural tumor suppressor gene,...

2013-04-25 20:23:59

New research reveals how the tumor suppressor p53 is shut down in metastatic melanoma -- and how it can be revived Cancer cells are a problem for the body because they multiply recklessly, refuse to die and blithely metastasize to set up shop in places where they don't belong. One protein that keeps healthy cells from behaving this way is a tumor suppressor named p53. This protein stops potentially precancerous cells from dividing and induces suicide in those that are damaged beyond...

2009-11-11 16:55:55

The small-molecule inhibitor nutlin-3 may be a viable treatment option for neuroblastoma patients with wild-type p53 activity, according to a new study published online November 10 in the Journal of the National Cancer Institute. In this study in mice, Tom Van Maerken, M.D., Center for Medical Genetics, Ghent University Hospital in Belgium, and colleagues evaluated the antitumor efficacy of nutlin-3, a potent and selective antagonist of the p53"“MDM2 interaction. Researchers found that...

Word of the Day
  • Boughs or branches.
  • Warbling of birds in trees.