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Latest Ohio State University Comprehensive Cancer Center Stories

2014-05-30 10:16:03

Ohio State University Wexner Medical Center A new study has discovered how resistance develops in patients taking ibrutinib, a new and highly effective drug for the treatment of chronic lymphocytic leukemia (CLL). The study was published in the New England Journal of Medicine and led by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James). It identifies gene mutations that...

2014-05-28 08:32:58

The Ohio State University Comprehensive Cancer Center and Moffitt Cancer Center create ORIEN to accelerate more precise cancer treatments, diagnostics and prevention methods TAMPA, Fla. and COLUMBUS, Ohio, May 28, 2014 /PRNewswire/ -- Two of North America's leading cancer centers, Moffitt Cancer Center and The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), today announced what is likely the...

2014-04-08 12:07:17

-NRAS is one of the most studied cancer-related genes. -This study found that the gene produces five variants, not just one form as thought. -The finding might help improve drugs for cancers that involve NRAS. A new study shows that a gene discovered 30 years ago and now known to play a fundamental role in cancer development produces five different gene variants (called isoforms), rather than just the one original form, as thought. The study of the NRAS gene by researchers at The Ohio...

HPV Virus Damages DNA
2013-11-08 09:36:45

redOrbit Staff & Wire Reports - Your Universe Online Human papillomavirus (HPV) can damage chromosomes and genes directly, researchers from the Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC – James) report in a new study. HPV is a virus that can cause anal, cervical, head and neck cancers, and according to experts, it produces two viral proteins (E6 and E7) that are involved in the development...

2013-06-20 23:30:02

Two clinical studies published in the New England Journal of Medicine with an accompanying editorial suggest that the novel agent ibrutinib shows real potential as a safe, effective, targeted treatment for adults with chronic lymphocytic leukemia (CLL) and for patients with mantle cell lymphoma (MCL). Both studies, co-led by researchers at The Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC —...

2013-02-08 14:27:40

-Triple-negative breast cancer is an aggressive form of breast cancer that has few treatment options; -This large-scale study shows that abnormal levels of small molecules called microRNA can be used to classify this malignancy into four subtypes; -The findings could lead to new ways to identify the best therapy for individual patients and to more effective therapies in the future. A new, large-scale study of triple-negative breast cancer shows that small molecules called microRNA can be...

2012-12-12 23:28:43

-People who develop chronic lymphocytic leukemia (CLL) are typically age 65 and older, but participants in CLL clinical trials are usually several years younger; -The age of CLL patients is not usually considered when determining treatment; -This study suggests that older and younger CLL patients require different therapy. Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the...

2012-06-20 00:44:06

-An estimated 10,200 Americans will die of acute myeloid leukemia (AML) in 2012, so new ways of treating the disease are needed. -This study uses a novel class of experimental drugs to halt a process that helps AML cells develop and survive. -The findings show that the agent is promising and should be considered for clinical trials testing. A novel family of experimental agents that blocks a molecule from shuttling proteins out of the cell nucleus might offer a new treatment for people...

2012-06-12 11:44:55

-People newly diagnosed with chronic leukemia must often wait to learn if they have a faster- or slower-progressing form of the disease. -This study identified a molecular marker that quickly helps to distinguish which form a patients has. -The findings could enable patients with aggressive disease to start treatment sooner. Researchers have identified a prognostic marker in the most common form of chronic leukemia that can help to distinguish which patients should start treatment...

2012-03-12 14:15:59

Researchers have identified a molecule that helps control the severity of graft-versus-host disease, a life-threatening complication for many leukemia patients who receive a bone-marrow transplant. The study, led by researchers with the Ohio State University Comprehensive Cancer Center — Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC — James), used an animal model and tissues from human patients to show that high levels, or over-expression, of...


Word of the Day
cock-a-hoop
  • Exultant; jubilant; triumphant; on the high horse.
  • Tipsy; slightly intoxicated.
This word may come from the phrase 'to set cock on hoop,' or 'to drink festively.' Its origin otherwise is unclear. A theory, according to the Word Detective, is that it's a 'transliteration of the French phrase 'coq a huppe,' meaning a rooster displaying its crest ('huppe') in a pose of proud defiance.' Therefore, 'cock-a-hoop' would 'liken a drunken man to a boastful and aggressive rooster.'
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