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Latest Oligodendrocyte Stories

2014-08-27 08:26:50

Dose Escalation Clinical Trial to Test Initial Safety and Activity of AST-OPC1 in Patient Population with the First Indication Targeted for Product Registration MENLO PARK, Calif., Aug. 27, 2014 /PRNewswire/ -- Asterias Biotherapeutics Inc. (OTCBB: ASTY) has received clearance from the U.S. Food and Drug Administration (FDA) to initiate a Phase 1/2a clinical trial of its product, AST-OPC1, in patients with complete cervical spinal cord injury. The approved trial follows the...

Sleep Boosts Cells That Protect Brain
2013-09-04 11:28:12

Brett Smith for redOrbit.com - Your Universe Online Scientists have long wondered about the precise biological needs that drive the body’s demand for sleep. While the need for a rest period may seem obvious, researchers are just beginning to uncover the underpinnings of our universal nightly ritual. According to new research in The Journal of Neuroscience, scientists at the University of Wisconsin, Madison have discovered that sleep allows the body to reinforce the production of...

2013-08-28 23:03:52

Findings Hold Promise for Developing Regenerative Therapies for Spinal Cord Injuries and Diseases Such as Multiple Sclerosis Sacramento, CA (PRWEB) August 28, 2013 Stem cell technology has long offered the hope of regenerating tissue to repair broken or damaged neural tissue. Findings from a team of UC Davis investigators have brought this dream a step closer by developing a method to generate functioning brain cells that produce myelin — a fatty, insulating sheath essential to normal...

Turning Stem Cells Into Brain Cells To Cure Multiple Sclerosis And Cerebral Palsy
2013-04-15 09:33:08

Lawrence LeBlond for redOrbit.com - Your Universe Online The painful, debilitating symptoms associated with myelin disorders, such as multiple sclerosis and cerebral palsy, may one day be avoided if new breakthroughs in medical science have anything to say about it. One such breakthrough by a team of scientists at Case Western Reserve School of Medicine (CaseMed) has discovered a technique that directly converts skin cells into a type of brain cells destroyed in patients with these myelin...

2013-04-01 11:21:28

Role of cells other than motor neurons much larger than anticipated Johns Hopkins scientists say they have evidence from animal studies that a type of central nervous system cell other than motor neurons plays a fundamental role in the development of amyotrophic lateral sclerosis (ALS), a fatal degenerative disease. The discovery holds promise, they say, for identifying new targets for interrupting the disease's progress. In a study described online in Nature Neuroscience, the...

2013-01-09 12:33:50

An experimental oral drug given to mice after a spinal cord injury was effective at improving limb movement after the injury, a new study shows. The compound efficiently crossed the blood-brain barrier, did not increase pain and showed no toxic effects to the animals. "This is a first to have a drug that can be taken orally to produce functional improvement with no toxicity in a rodent model," said Sung Ok Yoon, associate professor of molecular & cellular biochemistry at Ohio State...

Promising Nerve Research From Stem Cells Plus Nanofibers
2012-11-07 15:29:57

University of Michigan Health System Researchers coax cells to grow and myelinate along thin fibers, with potential use in testing treatments for neurological diseases Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury. He sees the pain, the loss of ability and the other effects that nerve-destroying conditions cause — and wishes he could give patients more...

2012-11-01 23:17:41

In a new study appearing this month in the Journal of Neuroscience, researchers have unlocked the complex cellular mechanics that instruct specific brain cells to continue to divide. This discovery overcomes a significant technical hurdle to potential human stem cell therapies; ensuring that an abundant supply of cells is available to study and ultimately treat people with diseases. “One of the major factors that will determine the viability of stem cell therapies is access to a safe...


Word of the Day
negawatt
  • A unit of saved energy.
Coined by Amory Lovins, chairman of the Rocky Mountain Institute as a contraction of negative watt on the model of similar compounds like megawatt.