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Latest Oligodendrocyte Stories

2012-06-04 17:21:14

Some neurological conditions such as multiple sclerosis and cerebral palsy are associated with the inability to repair the chronic destruction of myelin sheaths that surround the core of a nerve fiber and function to speed transmission of nerve impulses. To better understand the failure to remyelinate these nerves in disorders involving loss of these sheaths, researchers at Baylor College of Medicine examined how myelin forms during development. They found that a transcription factor known...

2012-05-10 14:00:27

Glial cells pass on metabolites to neurons Around 100 billion neurons in the human brain enable us to think, feel and act. They transmit electrical impulses to remote parts of the brain and body via long nerve fibers known as axons. This communication requires enormous amounts of energy, which the neurons are thought to generate from sugar. Axons are closely associated with glial cells which, on the one hand, surround them with an electrically insulating myelin sheath and, on the other...

2012-04-18 22:02:36

Researchers at the Perinatology Research Branch of the National Institutes of Health, located at the Wayne State University School of Medicine and the Detroit Medical Center, have demonstrated that a nanotechnology-based drug treatment in newborn rabbits with cerebral palsy (CP) enabled dramatic improvement of movement disorders and the inflammatory process of the brain that causes many cases of CP. The findings strongly suggest that there may be an opportunity immediately after birth for...

2012-02-27 11:09:40

Millions of adults suffer from the incurable disease multiple sclerosis (MS). It is relatively certain that MS is an autoimmune disease in which the body's own defense cells attack the myelin in the brain and spinal cord. Myelin enwraps the nerve cells and is important for their function of transmitting stimuli as electrical signals. There are numerous unconfirmed hypotheses on the development of MS, one of which has now been refuted by the neuroimmunologists in their current research: The...

2011-10-13 11:32:22

Scientists have improved upon their own previous world-best efforts to pluck out just the right stem cells to address the brain problem at the core of multiple sclerosis and a large number of rare, fatal children´s diseases. Details of how scientists isolated and directed stem cells from the human brain to become oligodendrocytes — the type of brain cell that makes myelin, a crucial fatty material that coats neurons and allows them to signal effectively — were published...

2011-09-29 23:14:11

Study findings indicate a key step in the generation of white matter and understanding developmental disabilities Through the identification of a gene's impact on a signaling pathway, scientists at Children's National Medical Center continue to make progress in understanding the mechanics of a key brain developmental process: growth and repair of white matter, known as myelination. The study, published online in the September 2011 online edition of The Journal of Neuroscience, identified...

2011-09-26 11:20:43

Process paves way for research, possible treatments of multiple sclerosis and more Scientists at Case Western Reserve University School of Medicine found a way to rapidly produce pure populations of cells that grow into the protective myelin coating on nerves in mice. Their process opens a door to research and potential treatments for multiple sclerosis, cerebral palsy and other demyelinating diseases afflicting millions of people worldwide. The findings will be published in the online...

2011-09-08 20:50:09

Narcolepsy is a rare disorder characterized by an excessive urge to sleep at inappropriate times and places. Narcoleptics are also often subject to "cataplexy," a sudden muscle weakness that is triggered by strong emotions. Although most cases of narcolepsy are thought to be caused by complex mechanisms, a small percentage of cases are associated with unidentified inherited mutations. Now, a new study published by Cell Press on September 8th in the American Journal of Human Genetics uncovers...

2011-08-16 06:10:00

ATLANTA, Aug. 16, 2011 /PRNewswire/ -- Inhibikase Therapeutics, Inc., an emerging leader in infectious disease, announced today that it has received FDA clearance to commence a Phase II proof-of-concept trial for its lead compound IkT-001. IkT-001, a host-directed kinase inhibitor, is intended to clear JC polyomavirus (JCV) infection, the causative agent of Progressive Multifocal Leukoencephalopathy (PML). This proof-of-concept trial will be conducted in multiple sclerosis (MS)...

2010-11-17 22:20:45

By tracking the fate of a group of immature cells that persist in the adult brain and spinal cord, Johns Hopkins researchers discovered in mice that these cells undergo dramatic changes in ALS, also known as Lou Gehrig's disease. A study reported November 17 online in Neuron shows that these cells, called NG2+, grow and expand rapidly during early life, eventually morphing into mature nervous system cells called oligodendrocytes. These "oligos" help speed the transmission of electrical...


Word of the Day
tesla
  • The unit of magnetic flux density in the International System of Units, equal to the magnitude of the magnetic field vector necessary to produce a force of one newton on a charge of one coulomb moving perpendicular to the direction of the magnetic field vector with a velocity of one meter per second. It is equivalent to one weber per square meter.
This word is named for Nikola Tesla, the inventor, engineer, and futurist.