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Latest Oligodendroglioma Stories

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2011-01-08 11:30:00

Scientists have identified the type of cell that is at the origin of brain tumors known as oligodendrogliomas, which are a type of glioma "“ a category that defines the most common type of malignant brain tumor.In a paper published in the December 2010 issue of the journal Cancer Cell, investigators found that the tumor originates in and spreads through cells known as glial progenitor cells "“ cells that are often referred to as "daughter" cells of stem cells. The work comes at a...

2011-01-06 13:43:36

New research shows that loss of a gene called NFKBIA promotes the growth of glioblastoma multiforme, the most common and deadly form of brain cancer, and suggests that therapies that stabilize this gene may improve survival for certain glioblastoma patients. The study was published recently in the New England Journal of Medicine. "We show that NFKBIA status may be an independent predictor of survival in certain patients with glioblastoma," says senior coauthor Dr. Arnab Chakravarti, chair and...

2011-01-05 09:04:37

(Ivanhoe Newswire) -- The deletion of a gene called NFKBIA may cause glioblastoma, the most common and malignant brain cancer. Researchers at the Stanford University School of Medicine recently discovered that the deletion of this gene, which is known to promote tumor development and resistance to therapy, was present in one out of every four glioblastoma cases. When NFKBIA is deleted, certain biochemical processes occur with striking similarity to an onset of glioblastoma, which often...

2010-12-23 16:54:43

A study fast-tracked for online publication Dec. 22 in the New England Journal of Medicine has identified an important gene deletion in up to one of every four cases of glioblastoma, the most common adult brain cancer. This deletion contributes to tumor development, promotes resistance to therapy and considerably worsens a patient's survival prospects. The deletion of the gene, known as NFKBIA, triggers biochemical processes similar to those resulting from a better-known aberration common in...

2010-12-14 23:50:19

For patients with glioma, the most common primary brain tumor, new findings may explain why current therapies fail to eradicate the cancer.  A UCSF-led team of scientists has identified for the first time that progenitor rather than neural stem cells underly a type of glioma called oligodendroglioma.  This distinction explains why oligodendroglioma is more responsive to therapy than other brain tumors such as glioblastoma multiforme. The finding is significant, the researchers say,...

2010-11-19 13:56:41

Data presented today from a pivotal, phase III randomized clinical trial for patients with recurrent glioblastoma tumors suggest that Tumor Treating Fields (TTF) therapy may increase median survival time and improve quality of life scores compared to best standard of care chemotherapy. Professor Zvi Ram, chairman of the Department of Neurosurgery at Tel-Aviv Sourasky Medical Center, presented the data at the Society for Neuro-Oncology (SNO) Annual Scientific Meeting. Physicians delivered the...

2010-11-19 12:00:00

MONTREAL, Nov. 19, 2010 /PRNewswire/ -- Data presented today from a pivotal, phase III randomized clinical trial for patients with recurrent glioblastoma tumors suggest that Tumor Treating Fields (TTF) therapy may increase median survival time and improve quality of life scores compared to best standard of care chemotherapy. Professor Zvi Ram, chairman of the Department of Neurosurgery at Tel-Aviv Sourasky Medical Center, presented the data at the Society for Neuro-Oncology (SNO) Annual...

2010-10-04 23:07:28

A new vaccine added to standard therapy appears to offer a survival advantage for patients suffering from glioblastoma (GBM), the most deadly form of brain cancer, according to a study from researchers at Duke University Medical Center and The University of Texas MD Anderson Cancer Center. The vaccine also knocks out a troublesome growth factor that characterizes the most aggressive form of the disease. "About a third of all glioblastomas are fueled by a very aggressive cancer gene, called...

2010-06-05 08:00:00

CHICAGO, June 5 /PRNewswire/ -- Data from the first phase III clinical trial of NovoCure's NovoTTF device for treatment of patients with recurrent glioblastoma (GBM) were presented today as a late breaking abstract during the Neuro-Oncology session at the American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago. Study results show that NovoTTF, a novel, non-invasive, portable medical device, may be as or more effective than the best available chemotherapies for GBM, but...

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2010-05-18 10:28:23

Researchers have identified an important cancer gene that could lead to more effective drugs being developed to fight pediatric high grade glioma, a disease which currently has a poor prognosis. The discovery, published in the Journal of Clinical Oncology, was one of a number of significant genetic differences found between the adult and youth form of the disease. Gliomas are the most common brain tumor in children. Clinicians and scientists at The Institute of Cancer Research (ICR) and The...


Word of the Day
lunula
  • A small crescent-shaped structure or marking, especially the white area at the base of a fingernail that resembles a half-moon.
This word is a diminutive of the Latin 'luna,' moon.
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