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Latest Oncolytic virus Stories

2011-10-18 09:49:54

First to discover probe human genome to augment oncolytic therapy Oncolytic virology uses live viruses to sense the genetic difference between a tumor and normal cell. Once the virus finds a tumor cell, it replicates inside that cell, kills it and then spreads to adjacent tumor cells to seed a therapeutic "chain reaction". As reported in today's issue of Cancer Cell, Dr. David Stojdl, a scientist from the Children's Hospital of Eastern Ontario Research Institute at the University of Ottawa...

2011-10-03 21:50:45

They have been around since the dawn of time and are a model of evolutionary success: viruses. Viruses are extremely adaptable but they have a problem: They cannot reproduce, so they smuggle their genes into suitable host cells. In the case of some viruses, the viral DNA has to enter the cell nucleus to reproduce. This has been known for almost 50 years. We know, for instance, that the adenovirus disassembles its protein shell in the first step. Just how the DNA is exposed and infiltrates the...

New Virus Shows Promise In Fighting Cancer
2011-08-31 13:07:25

  Researchers have engineered a virus that can selectively target cancer cells throughout the body. According to the team, the virus attacked only tumors during a small trial on 23 patients, leaving the healthy tissue alone. Researchers said the findings could one day "truly transform" therapies. Scientists modified the vaccinia virus, which is famous for being used to develop a smallpox vaccine. The virus is dependent on a chemical pathway in order to replicate. It was...

2011-08-26 11:02:28

PVRL4 (Nectin 4) is a receptor for measles virus Canadian researchers have discovered that a tumor cell marker is a receptor for measles virus, suggesting the possible use of measles virus to help fight cancer. Their findings appear in the Open Access journal PLoS Pathogens on August 25th. Viruses cause infection by attaching to specific proteins on cell surfaces called receptors. Dr. Chris Richardson of Dalhousie Medical School in Halifax, Nova Scotia, Canada and colleagues found that...

2011-08-11 06:00:00

SAN FRANCISCO, Aug. 11, 2011 /PRNewswire/ -- Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic virus products for cancer, today announced that it has completed a successful private placement financing with gross proceeds of approximately $8.6 million. Proceeds from this transaction will be primarily used to advance the late-stage clinical development of Jennerex's lead product candidate,...

2011-08-02 06:00:00

CALGARY, Aug. 2, 2011 /PRNewswire/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that an international team of researchers has reported on a study in the online version of Molecular Therapy, a publication of The American Society of Gene and Cell Therapy, investigating the timing of chemotherapy delivery that optimizes the efficacy of systemic REOLYSIN(®). The paper is entitled "Precise Scheduling of Chemotherapy Primes VEGF-producing...

2011-08-02 01:00:00

SAN FRANCISCO, Aug. 2, 2011 /PRNewswire/ -- Jennerex, Inc., a private clinical-stage biotherapeutics company focused on the development and commercialization of first-in-class targeted oncolytic products for cancer, today announced that positive results from a proof-of-concept clinical trial using JX-594 to treat patients with metastatic melanoma were published in the peer-reviewed journal Molecular Therapy. "This clinical trial in metastatic melanoma provides additional key information...


Word of the Day
endocarp
  • The hard inner (usually woody) layer of the pericarp of some fruits (as peaches or plums or cherries or olives) that contains the seed.
This word comes from the Greek 'endon,' in, within, plus the Greek 'karpos', fruit.
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