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Latest Optic nerve Stories

2012-04-04 12:19:11

Working in mice, scientists at Washington University School of Medicine in St. Louis have devised a treatment that prevents the optic nerve injury that occurs in glaucoma, a neurodegenerative disease that is a leading cause of blindness. Researchers increased the resistance of optic nerve cells to damage by repeatedly exposing the mice to low levels of oxygen similar to those found at high altitudes. The stress of the intermittent low-oxygen environment induces a protective response called...

2012-03-19 16:59:32

Jackson Laboratory researchers identify new damaging mechanism Jackson Laboratory researchers have demonstrated that a single, targeted x-ray treatment of an individual eye in young, glaucoma-prone mice provided that eye with apparently life-long and typically complete protection from glaucoma. In research published March 19 in the Journal of Clinical Investigation, Gareth Howell, Ph.D., Simon John, Ph.D., (professor and Howard Hughes Medical Investigator) and colleagues also used...

2012-03-19 16:56:50

Glaucoma is one of the leading causes of vision loss and blindness worldwide. In glaucoma patients, the optic nerve, which relays information from the eye to the brain, is damaged, though the molecular cause of nerve damage is unclear. Dr. Simon John, from Tufts University in Boston, and colleagues specifically wanted to understand the earliest events that lead to optic nerve damage in glaucoma. Using a mouse model of the disease, the researchers showed that inflammatory immune cells called...

2012-03-14 12:55:12

For the first time, scientists at the University of Wisconsin-Madison have made early retina structures containing proliferating neuroretinal progenitor cells using induced pluripotent stem (iPS) cells derived from human blood. And in another advance, the retina structures showed the capacity to form layers of cells — as the retina does in normal human development — and these cells possessed the machinery that could allow them to communicate information. (Light-sensitive...

2012-03-07 13:49:33

A new paradigm to explain glaucoma is rapidly emerging, and it is generating brain-based treatment advances that may ultimately vanquish the disease known as the "sneak thief of sight." A review now available in Ophthalmology, the journal of the American Academy of Ophthalmology, reports that some top researchers no longer think of glaucoma solely as an eye disease. Instead, they view it as a neurologic disorder that causes nerve cells in the brain to degenerate and die, similar to what...

2012-02-09 00:51:31

A new study identifies specific cell-stress signaling pathways that link injury of the optic nerve with irreversible vision loss. The research, published by Cell Press in the February 9 issue of the journal Neuron, may lead to new strategies that will help to protect vulnerable neurons in the retina after optic nerve damage and diseases. Retinal ganglion cells (RGCs) send visual information from the retina to the brain through long processes called axons. The axons of the RGCs are bundled...

2012-01-05 11:48:44

Glaucoma is a major cause of vision loss in the United States, affecting about 2.2 million Americans. The National Eye Institute (NEI) leads research toward better prevention, detection, and treatment of this often silent but devastating disease. During Glaucoma Awareness Month, NEI highlights research advances, showcases education and awareness efforts, and reminds Americans that early detection and treatment is the best way to prevent vision loss. NEI advises all Americans at risk of...

2011-09-29 14:34:22

Study suggests glaucoma screenings are happening too late Glaucoma is the second leading cause of blindness worldwide. Although it can be treated, new research shows Canadians may not be doing enough to protect themselves. According to a new study by Lawson Health Research Institute's Dr. Cindy Hutnik, many Canadian glaucoma patients are not screened until the disease has reached moderate or advanced stages. Glaucoma is known as the "silent thief of sight." It slowly and irreversibly...


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